Pseudomonas mesophilica Cutaneous Infection in an Immunocompetent Patient

Methylobacterium mesophilicum cellulitis and lymphangitis following a dog bite

“…Infections were subacute and characterized by a mild clinical course. Clear or suggestive history of environmental exposure to M. mesophilicum was identified in some cases such as a 33-year-old woman who had infected Hickman catheter following handling of earthworms; a 28-year-old woman who had chronic skin ulcers following bathing in a river; and a gardener who had recurrent peritonitis possibly due to contamination of the peritoneal dialysis catheter [11,13,14]. However, history suggestive of environmental contamination was absent in most cases [11].…”

Methylobacterium bacteremia in AIDS

“…Additionally, several methylobacterium infections have been reported in leukemia patients after bone marrow transplantation [3]. One case of cutaneous infection was reported in an leukemia patient [5], and one case from a patient with AIDS [3]. Here we describe a case of methylobacterium bacteremia in a patient with AIDS.…”

“…Methylobacterium species are saprophytic, pink‐pigmented, Gram‐negative bacilli that rarely cause human disease [1–3], Most cases of human infection have been in patients who are immunocompromised due to severe underlying disease. or are im‐munosuppressed; however, one case of cutaneous methylobacterium infection has been reported in an immunocompetent individual [5]. The genus Methylobacterium includes eight species, Methylobacterium extorquens, M.fujisawaense, M. mesophilicum, M.organophilum, M. radiolerans, M.rhodinum, M. rhodesianum and M. zatmanii [2].…”

Pink-pigmented Non-fermentative Gram-negative Rods Associated with Human Infections: a Clinical and Diagnostic Challenge

“…Chronic cutaneous infections in healthy persons ranging from subcutaneous nodules of the finger to extensive ulcerative lesions of the buttocks have been described [2,24]. In addition to recovery of methylobacteria from biopsy tissue, serum from one individual had a 1:80 agglutinating antibody titer against the infecting agent [2].…”

“…In addition to recovery of methylobacteria from biopsy tissue, serum from one individual had a 1:80 agglutinating antibody titer against the infecting agent [2]. In another instance, a female developed abrasions on her arms while swimming or bathing in Ecuadorian rivers; this appeared to be the precipitating factor for her dermatologic illness [24]. Other well-documented infections associated with Methylobacterium include peritonitis [25] and synovitis [26].…”