Pseudomonas in a Glasgow Baby Unit

Henderson, A.; Maclaurin, J.; Scott, J. M

doi:10.1016/s0140-6736(69)90071-3

Cited by 28 publications

(10 citation statements)

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“…These observa tions support the hypothesis of an infectious etiology. Other outbreaks have been reported in association with a single agent such as Pseudomonas aeruginosa [19,20] In our study, a corona virus was found in 5 out of 8 cases where electron-microscopic examination of the stools was performed. Its pathogenicity is well known in the calf (lethal bloody diarrhea).…”

Section: Discussionsupporting

confidence: 59%

Necrotizing Enterocolitis in Full-Term Newborns

Gamarra¹,

Helardot²,

Moriette³

et al. 1983

Neonatology

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During a 17-month period, 19 full-term newborn infants were hospitalized for necrotizing enterocolitis (NEC). 10 of these infants had no apparent risk factors. Only 7 suffered acute fetal distress. 16 of the 19 infants were born in the same hospital. Toxicological and bacteriological investigations of possible cause revealed no specific agent. Virological analysis of 8 stool samples revealed the presence of corona virus in 5 of the 8.

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Section: Discussionsupporting

confidence: 59%

Necrotizing Enterocolitis in Full-Term Newborns

Gamarra¹,

Helardot²,

Moriette³

et al. 1983

Neonatology

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“…pneumoniae, all 3 organisms having been reported previously as the single organism involved in an outbreak of NEC (8)(9)(10).…”

Section: Discussionmentioning

confidence: 97%

Necrotizing Enterocolitis: A 15‐Year Experience

Leong

Drew

1987

Aust NZ J Obst Gynaeco

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Eighty-seven infants (0.13% of livebirths) developed necrotizing enterocolitis (NEC) during a 15-year period at the Mercy Maternity Hospital, Melbourne. The disease was associated with 23 deaths, representing a mortality rate of 26.4% and comprising 2.6% of all neonatal deaths. The incidence of NEC increased from 0.07% of all livebirths for the years 1971-1974 to 0.25% for the 19-month period from January, 1984 to July, 1985. The mean age at onset was 9.9 days with an inverse relationship between birth-weight and age of onset of the disease. The mothers of the infants who developed NEC belonged to a significantly higher risk obstetric population; gestational diabetes was identified in 3 of 28 mothers (10.6%) having glucose tolerance tested, and 1 other patients was a known diabetic. Subnormal oestriol excretion was detected in 15 of 45 patients tested, treble the overall hospital incidence. Of the 87 infants, 26 (29.9%) were VLBW (birth-weight less than 1,500 g), 5 were term (5.7%) and 9 (10.3%) were small for gestational age. The mean gestational age was 34.7 weeks and mean birth-weight was 1,988 g. Sixty-seven (77%) infants received medical treatment alone and 20 (23%) also received surgical treatment. Sequelae which developed in survivors were colonic strictures (4), fistulas (2) and the short-gut syndrome (1).

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“…7 and 8) grew pure cultures of klebsiellae and pseudomonads respectively ; since these were the only Gramnegative aerobic rods cultured they were presumed to be responsible for the disease. Apart from E. coli, other organisms have also been incriminated as a cause of gastroenteritis and diarrhoea ; for example, klebsiellae in infants (Olarte et al, 1961) and in patients with tropical sprue (Klipstein et al, 1973) and pseudomonads in infants (Henderson, Maclaurin and Scott, 1969 ;Wadstrom et al, 1976;Ferrao and Mavinkurve, 1977). These organisms were present in the jejunum in several of the infants, either alone or with other organisms, and in certain instances may have caused the illness.…”

Section: Discussionmentioning

confidence: 99%