Pseudomonas Corneoscleral Ulcers

Hessburg, Philip C.

doi:10.1016/0002-9394(82)90430-5

Cited by 8 publications

(4 citation statements)

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“… 27 Due to poor success rate with medical therapy alone, clinicians resorted to other modalities such as subpalpebral irrigation with antibiotics, carbon dioxide laser, conjunctival recession and cryotherapy with variable success rates. 3 32 In our series complete resolution was seen in all the six cases with surgical debridement, topical and systemic antibiotics. Topical steroids along with antibiotics were used in two cases.…”

Section: Discussionsupporting

confidence: 53%

Risk factors and clinical outcomes of bacterial and fungal scleritis at a tertiary eye care hospital

Reddy¹,

Murthy²,

Reddy

et al. 2015

Middle East Afr J Ophthalmol

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Purpose:The aim was to analyze demographics, risk factors, pathogenic organisms, and clinical outcome in cases with microbiologically proven bacterial or fungal scleritis.Materials and Methods:Retrospective review of all the medical records of patients with microbiologically proven infectious scleritis examined from March 2005 to December 2009 in the cornea services of L. V. Prasad Eye Institute, Hyderabad, India was done.Results:Forty-two eyes of 42 patients were included in this study. The mean age at presentation was 48.52 ± 14.10 years (range: 12-70). Surgery was the major risk factor seen in 24 eyes (58.5%). Scleral infection was noted after vitreoretinal surgery (with scleral buckle) in 15 eyes, cataract surgery in 3 eyes, pterygium surgery in 3 eyes, corneoscleral tear repair and scleral buckle surgery in 3 eyes. Sixteen eyes (39%) were on systemic or topical steroids at the time of presentation. History of injury was noted in 9 eyes (22%) and diabetes mellitus in 7 patients (17%). Associated keratitis was noted in 9 eyes (21.4%). The scleral abscess was unifocal in 33 eyes (78.5%), multifocal in 6 eyes (14.2%) and diffuse in 3 eyes (7.14%). The final follow-up ranged from 24 days to 37 months. The final visual acuity was better in 18 eyes (42.8%), stable in 13 (30.9%), and deteriorated in 7 eyes (16.6%). Recurrence was seen in 4 eyes (9.5%).Conclusions:Surgery is a major risk factor for infectious scleritis in our series. Fungus was the most common organism isolated. Thorough debridement and intensive use of medications have improved the outcome.

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Section: Discussionsupporting

confidence: 53%

Risk factors and clinical outcomes of bacterial and fungal scleritis at a tertiary eye care hospital

Reddy¹,

Murthy²,

Reddy

et al. 2015

Middle East Afr J Ophthalmol

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“…Numerous management options have been described including topical fortified antibiotics, subconjunctival antibiotics, cryotherapy, lamellar or penetrating corneoscleral graft, and subpalpebral irrigation to allow for continuous delivery of highly concentrated antibiotics. 40 Because corneoscleral grafts performed in the active phase of infection often result in necrosis, sloughing, or rejection, and because topical and subconjunctival antibiotics frequently fail to control infection, our greatest success in these cases has come from subpalpebral irrigation with broadspectrum antibiotics before a corneoscleral graft. A scleral protection shell is placed over the eye, and 3 mL of 2% lidocaine with epinephrine is injected into the upper eyelid.…”

Section: N Etiology and Pathogenesismentioning

confidence: 99%

The Diagnosis and Management of Anterior Scleritis

Albini¹,

Rao²

2005

International Ophthalmology Clinics

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“…If microorganisms are not isolated despite repeated testing, and histopathological study reveals an inflammatory picture, autoimmune scleritis must be suspected, and therapy with oral corticosteroids, immunosuppressive, or biologics should be considered under antibiotic coverage as a last resort. Numerous management options have been described including topical fortified antibiotics, subconjunctival antibiotics, cryotherapy, lamellar or penetrating corneoscleral graft, and subpalpebral irrigation to allow for continuous delivery of highly concentrated antibiotics [35]. Indications for surgery in either infectious or autoimmune scleritis include biopsy for suspected infectious scleritis, repair of corneal and scleral defects, repair of globe perforation, and repair of uveal prolapse with impending perforation in necrotizing scleritis.…”

Section: Managementmentioning

confidence: 99%

Untitled

2023

TOOAJ

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Scleritis refers to chronic painful inflammatory diseases of the sclera that can also involve cornea and underlying uveal tract. Pathogenic mechanisms in scleritis are poorly understood, but enzymatic degradation of collagen fibrils by infiltrating leukocytes seems to be a key feature. Although a majority of these cases are immune mediated and at least half of these are associated with underlying systemic illnesses. About 5-10 % of cases are due to infectious causes. Infectious scleritis is often initially managed as autoimmune due to the similarity of its presentation leading to poor outcome. Careful clinical history taking, detailed ocular examination, appropriate investigation and timely intervention has improved the long-term outcome for patients with this disease.

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Pseudomonas Corneoscleral Ulcers

Cited by 8 publications

References 0 publications

Risk factors and clinical outcomes of bacterial and fungal scleritis at a tertiary eye care hospital

Risk factors and clinical outcomes of bacterial and fungal scleritis at a tertiary eye care hospital

The Diagnosis and Management of Anterior Scleritis

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