Pseudolesion of the Liver on Gadoxetate Disodium-Enhanced MR Images Obtained After Transarterial Chemoembolization for Hepatocellular Carcinoma: Clinicoradiologic Correlation

Abstract

The prevalence and appearance of pseudolesions differ at different intervals from TACE. Radiologists need to recognize the clinicoradiologic characteristics to differentiate pseudolesions from true residual or recurrent HCC.

Hepatic reaction dose for parenchymal changes on Gd‐EOB‐DTPA‐enhanced magnetic resonance images after stereotactic body radiation therapy for hepatocellular carcinoma

“…Shinagawa et al . reported that parenchymal changes can occur after TACE . However, our results showed good data fit, with R 2 values ranging from 0.76 to 0.99, and the patterns of reduced parenchymal enhancement were similar between previous treated and untreated lesions.…”

Surveillance and Diagnostic Algorithm for Hepatocellular Carcinoma Proposed by the Liver Cancer Study Group of Japan: 2014 Update

“…It has actually become common to encounter cases where hypervascular HCC or nodule-in-nodule HCC that is undetectable by MDCT is detected in a routine screening by EOB-MRI because of early enhancement in the arterial phase or clear hypointensity in the hepatobiliary phase [11,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89,90,91,92,93,94,95,96,97,98,99,100,101,102,103]. Furthermore, studies comparing the diagnostic performance of EOB-MRI and MDCT for hypervascular HCC have shown that EOB-MRI is superior or, at the very l...…”

Evaluation of tumor recurrence after superselective conventional transcatheter arterial chemoembolization for hepatocellular carcinoma: Comparison of computed tomography and gadoxetate disodium‐enhanced magnetic resonance imaging

“…Additionally, it is reported that gadoxetate disodium‐enhanced MRI can predict the patient prognosis because hyperintense HCC in the hepatobiliary phase have biologically less aggressive features than those of hypointense HCC . On the other hand, gadoxetate disodium‐enhanced MRI frequently shows pseudolesions in follow‐up studies after cTACE, as well as artifacts in the arterial phase of dynamic study. In a report by Shinagawa et al.…”