Pseudogout Syndrome in Hospital Patients

O’Duffy, J. Desmond

doi:10.1001/jama.1973.03230010020004

Cited by 28 publications

(6 citation statements)

References 16 publications

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“…In this small group of patients the response time to colchicine was similar to that associated with the use of other therapeutic modalities, such as synovial aspiration with intraarticular injections of corticosteroids or oral administration of nonsteroidal antiinflammatory drugs (6). However the use of these other antiinflammatory drugs is sometimes militated against by the presence of associated conditions commonly seen in the age group of these patients.…”

Section: Discussionsupporting

confidence: 53%

“…A variety of medications have been recommended for the treatment of the acute arthritis of pseudogout, particularly nonsteroidal antiinflammatory drugs, joint aspiration, and installation of corticosteroids (6). The effect of colchicine has been traditionally considered "unpredictable" (3).…”

Section: Discussionmentioning

confidence: 99%

“…The effect of colchicine has been traditionally considered "unpredictable" (3). In one retrospective study, various forms of therapy gave an excellent response within 24 to 48 hours, whereas colchicine alone resulted in "slower resolution of synovitis over 2 to 7 days" (6). McCarty commented that although it was not known whether the symptoms and signs of pseudogout respond to colchicine, "we think they do not" (2).…”

Section: Discussionmentioning

confidence: 99%

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Intravenous colchicine in the treatment of acute pseudogout

Tabatabai

Cummings

1980

Arthritis & Rheumatism

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Section: Discussionsupporting

confidence: 53%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Intravenous colchicine in the treatment of acute pseudogout

Tabatabai

Cummings

1980

Arthritis & Rheumatism

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“…However, one non-randomised controlled trial found that intra-articular steroids in hospitalised patients was associated with a quicker onset of relief compared with oral corticosteroids. 55 Although far from the ideal level of evidence, colchicine, NSAIDs and corticosteroids are regularly used in the treatment of acute CPPD, and most clinicians are comfortable in choosing one of these agents when acceptable low-level risk is present depending on individual patient characteristics.…”

Section: Treatmentmentioning

confidence: 99%

Diagnosis and Treatment of Calcium Pyrophosphate Deposition (CPPD) Disease: A Review

Cowley¹,

McCarthy²

2023

OARRR

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Calcium Pyrophosphate Dihydrate (CPPD) crystal-related arthropathies are a common cause of acute and chronic arthritis caused by the deposition of calcium pyrophosphate crystals in joints and soft tissues, resulting in inflammation and joint damage. They present with a wide spectrum of clinical manifestations and often present challenges to diagnosis and management as they commonly affect older co-morbid patients. The challenges are compounded by a lack of a well-defined description of CPPD. However, an international expert-driven process is underway to develop CPPD classification criteria. Treatment is also problematic as unlike gout, there are no agents available that decrease the crystal burden. Treatment options have often been extrapolated from gout treatment pathways without having extensive trials or a solid evidence base. It is hoped the new CPPD classification guidelines will contribute to large multicentre studies, with well-defined patient cohorts, which will facilitate the production of high-quality evidence to guide the management of this condition. Here, we discuss the barriers and facilitators in diagnosing and treating CPPD-related arthropathy.

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“…While invasive procedures such as surgery are known to present a risk of acute pseudogout, reports of occurrence after endoscopic procedures are scarce [6][7][8][9]. Here we present the case of CDS which occurred after endoscopic submucosal dissection (ESD) for early gastric cancer.…”

Section: Introductionmentioning

confidence: 96%

Crowned Dens Syndrome Occurring after Endoscopic Submucosal Dissection for Early Gastric Cancer

Okamoto¹,

Ikeya²,

Fukuda³

2021

Case Rep Gastroenterol

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Crowned dens syndrome (CDS) is a rare form of pseudogout which causes acute neck pain due to calcium pyrophosphate dehydrate deposition surrounding the odontoid process, commonly causing neck pain with rigidity. While invasive procedures such as surgery are known to present a risk of acute pseudogout, reports of occurrence after endoscopic procedures are scarce. We report the case of a 75-year-old man who presented with sudden neck pain after endoscopic submucosal dissection (ESD) for gastric cancer. He could nod but could not rotate his head. Computed tomography showed calcifications surrounding the odontoid process consistent with CDS. Prolonged dietary restrictions and proton pump inhibitor use following the ESD procedure may have caused hypomagnesemia, a precipitating factor for CDS. We prescribed colchicine 1 mg/day and symptoms resolved completely in 3 days. This is the first report of CDS after ESD. CDS should be included in the differential diagnosis of neck pain after endoscopic procedures.

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Pseudogout Syndrome in Hospital Patients

Cited by 28 publications

References 16 publications

Intravenous colchicine in the treatment of acute pseudogout

Intravenous colchicine in the treatment of acute pseudogout

Diagnosis and Treatment of Calcium Pyrophosphate Deposition (CPPD) Disease: A Review

Crowned Dens Syndrome Occurring after Endoscopic Submucosal Dissection for Early Gastric Cancer

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