Pseudofolliculitis of the Beard

Strauss, John S.; Kligman, Albert M.

doi:10.1001/archderm.1956.01550110077016

Cited by 78 publications

(28 citation statements)

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“…These ingrowing hairs initiate a foreign body reaction producing erythematous papules and pustules that may heal with or without scarring and may even produce keloid formation. The primary lesions normally subside upon discontinuance of shaving or employing alternative grooming measures (Dubreuilh, 1922;Strauss and Kligman, 1956). Compared to Caucasian males, black males are distinctly more susceptible to developing PFB (Fig 1) due to their genetic predisposition for strongly curved hairs.…”

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confidence: 99%

“…Compared to Caucasian males, black males are distinctly more susceptible to developing PFB (Fig 1) due to their genetic predisposition for strongly curved hairs. These hairs show a concavity towards the epidermis and therefore have a much higher tendency to reenter the skin than straight or wavy hairs (Strauss and Kligman, 1956;Rook and Dawber, 1982;Kauvar, 2000). Furthermore, facial hair patterns have recently been identified as an additional genetic factor involved in the PFB process.…”

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An Unusual Ala12Thr Polymorphism in the 1A α-Helical Segment of the Companion Layer-Specific Keratin K6hf: Evidence for a Risk Factor in the Etiology of the Common Hair Disorder Pseudofolliculitis Barbae

Winter

Schissel

Parry

et al. 2004

Journal of Investigative Dermatology

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Pseudofolliculitis barbae (PFB) is a common hair disorder characterized by a pustular foreign body inflammatory reaction that is induced by ingrown hairs of the facial and submental (barbea) regions after regular shaving. It occurs predominantly in black males, while it is rather rare and usually far less severe in Caucasian males. Black individuals have a higher propensity of developing PFB due to their genetic predisposition for curly hair which inherently possesses a much higher risk of growing back into the skin than straight or wavy hair. The PFB process is, however, not gender dependent nor restricted to the face, but can occur in any skin region once regular shaving, plucking, or other traumatic means of hair removal are instituted. Through a family study and a large-scale investigation of randomly sampled PFB-affected and -unaffected individuals, this study demonstrates that an unusual single-nucleotide polymorphism, which gives rise to a disruptive Ala12Thr substitution in the 1A alpha-helical segment of the companion layer-specific keratin K6hf of the hair follicle, is partially responsible for the phenotypic expression and represents an additional genetic risk factor for PFB.

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An Unusual Ala12Thr Polymorphism in the 1A α-Helical Segment of the Companion Layer-Specific Keratin K6hf: Evidence for a Risk Factor in the Etiology of the Common Hair Disorder Pseudofolliculitis Barbae

Winter

Schissel

Parry

et al. 2004

Journal of Investigative Dermatology

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“…Thus far, none of these theories has been proven, and all are based on circumstantial evidence. The notion that lesions of AK are caused by ingrowing hairs, 13 analogous to the situation in pseudofolliculitis barbae, 14 persists, despite the fact that there is no evidence to support this hypothesis. 3 There is considerable evidence to the contrary, 15 and our findings conclusively separate the pathogenic mechanisms of AK and pseudofolliculitis barbae.…”

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Acne Keloidalis Is a Form of Primary Scarring Alopecia

Sperling¹,

Homoky²,

Pratt³

et al. 2000

Arch Dermatol

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“…Pseudo-folliculitis usually affects the beard area, when it is known as pseudo-folliculitis barbae. It is known as pseudo-folliculitis not only because it is clinically confused with folliculitis but also because a pseudo-follicle forms as the in-growing beveled hair tip proceeds into the dermis and epithelial cells downgrow in an attempt to ensheath it[25] [Figure 11]. …”

Section: Pseudo-conditions/diseasesmentioning

confidence: 99%

"Pseudo" nomenclature in dermatology: What′s in a name?

Ghosh

Jain

2013

Indian J Dermatol

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In the bewildering array of scientific nomenclature in the medical field, it is important to use correct terminology, know their aberrations and the reason behind a specific terminology. This paper is an attempt towards compiling all the pseudo-nomenclatures coined in dermatology, in order to make it easier to retain and recollect these pseudo names, signs, morphology, diseases, and conditions. It is also imperative to know the true entities that these pseudo names masquerade as, so as to understand the explanation for assigning the term ‘pseudo’ to these conditions. A total of 52 pseudo-terms have been compiled here in reference to dermatology. Most of these pseudo-nomenclatures were coined due to some clinical or histopathological resemblance to the true conditions, while some were premature conclusions drawn from a flawed understanding of the basic nature of the condition. Clear understanding of each of these terms and the explanation behind them being pseudo will enable a dermatologist to avoid misdiagnosis and needless confusion.

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Pseudofolliculitis of the Beard

Cited by 78 publications

References 7 publications

An Unusual Ala12Thr Polymorphism in the 1A α-Helical Segment of the Companion Layer-Specific Keratin K6hf: Evidence for a Risk Factor in the Etiology of the Common Hair Disorder Pseudofolliculitis Barbae

An Unusual Ala12Thr Polymorphism in the 1A α-Helical Segment of the Companion Layer-Specific Keratin K6hf: Evidence for a Risk Factor in the Etiology of the Common Hair Disorder Pseudofolliculitis Barbae

Acne Keloidalis Is a Form of Primary Scarring Alopecia

"Pseudo" nomenclature in dermatology: What′s in a name?

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