Pseudoexfoliation glaucoma in Greece

Konstas, A. G. P.; Allan, Donald

doi:10.1038/eye.1989.116

Cited by 39 publications

(39 citation statements)

References 35 publications

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“…Two studies where the data were population corrected and subsequently compared with age matched controls, show females being affected by the disorder more frequently than males (Aasved 1969;Hiller et al 1982). However, this preponderance of females has not been confirmed in other populations (Bartholomew 1973;Taylor 1979;Forsius 1979;Konstas & Allan 1989) and large ophthalmic cohorts (Colin et al 1988;Montanes et al 1989). In the present study no difference was found for sex between the 3 groups.…”

Section: Discussionmentioning

confidence: 99%

“…In that study, Lindberg documented changes consistent with the diagnosis of the disorder in 28 out of 142 cataractous patients. Overall, most published reports have suggested a higher prevalence of EXS in cataract patients (Horven 1966;Taylor et al 1977;Roth & Epstein 1980;Madden & Crowley 1982;Forsius 1988;Konstas & Allan 1989). In the Framingham study, however, although an association between exfoliation and lens opacities was found in an age-adjusted population cohort, this was not statistically significant (Hiller et a].…”

mentioning

confidence: 97%

“…1982). Similarly, the frequency of lens opacities in selected exfoliation cohorts differs according to the popu-lation studied between 20 and 93% (Tarkkanen 1962;Horven 1966;Layden & Shaffer 1974;Taylor 1980;Madden & Crowley 1982;Konstas & Allan 1989;Stefaniotou et al 1990; Montanes et al 1989). Furthermore, 2 studies identified significant differences in the type of cataract in patients with EXS (Seland & Chylack 1982;Fama et al 1993).…”

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confidence: 99%

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Frequency of exfoliation syndrome in Greek cataract patients

Konstas

Dimitrakoulias

Kourtzidou

et al. 1996

Acta Ophthalmologica Scandinavica

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The frequency of exfoliation syndrome (EXS) was investigated in a group of Greek patients undergoing extracapsular cataract surgery. Five hundred and nine (509) consecutive cataract patients without any other manifest ocular abnormality were prospectively examined for the presence of EXS. Patients were clinically divided into 3 groups: group I (EXS group) consisted of patients in whom exfoliation material deposition could be seen; Group II (possible EXS group) comprised patients who demonstrated a number of pigmentary signs and group III (normal subjects) comprised patients with senile cataract and no sign of EXS. EXS was found in 140 (28%) of our patients, possible EXS in 119 (23%) and the rest (49%) had no evidence of EXS. Patients with EXS were older (mean age 73.8) when compared to the possible EXS group (70 years) and the control group (64.7 years). The IOP was significantly higher in patients with EXS (mean 15.5 mmHg versus 14.3 mmHg in the other two groups). Blue irides were significantly more common in patients with EXS (19%) than in the possible EXS group (14%) and the controls (4%). EXS is common in Greek cataract patients and this study has identified a large group of patients who may be at an early stage of development of the condition. EXS may predispose to the development of cataract in Greek patients.

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Section: Discussionmentioning

confidence: 99%

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confidence: 97%

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confidence: 99%

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Frequency of exfoliation syndrome in Greek cataract patients

Konstas

Dimitrakoulias

Kourtzidou

et al. 1996

Acta Ophthalmologica Scandinavica

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“…The group of patients studied and the diagnostic methods employed have been reported previously (Konstas & Allan 1989). Briefly, 74 Greek patients, who underwent trabeculectomy for chronic open angle glaucoma in the University Eye Department, AHEPA Hospital, Thessaloniki were re-examined using 3 different methods in an attempt to determine the true prevalence of EXG in a Greek population who had undergone trabeculectomy.…”

Section: Methodsmentioning

confidence: 99%

Gonioscopic findings in Greek patients with exfoliation glaucoma

Konstas¹,

Dutton²

1991

Acta Ophthalmologica

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A prospective gonioscopic evaluation was carried out upon a cohort of Greek patients who had undergone trabeculectomy for open-angle glaucoma. Sixty-five patients were found to show clinical evidence of exfoliation glaucoma (EXG), whilst nine patients were deemed to have primary open angle glaucoma (POAG). The gonioscopic features of these eyes and of 43 non-operated eyes from the same patients with either exfoliation syndrome (EXS) or EXG are presented. The median degree of angle pigmentation was significantly higher in the operated eyes with EXG when compared with the POAG cases. In the operated eyes, deposition of exfoliation was found on the ciliary processes in 82% of cases and on the zonules in 52%.

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“…Therefore surgery is often indicated in EXG and is often successful in reducing IOP (Jerndal & Kriisa 1974, Konstas & Allan 1989, Konstas et al 1993b). However, the preoperative features and the long term effect of surgery upon the preservation of visual function have yet to be studied prospectively in a large cohort of patients.…”

mentioning

confidence: 99%

Preoperative features of patients with exfoliation glaucoma and primary open‐angle glaucoma. The AHEPA study

Konstas

Tsatsos

Kardasopoulos

et al. 1998

Acta Ophthalmologica Scandinavica

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ABSTRACT.Purpose: To describe and compare the preoperative characteristics of Greek patients with exfoliation glaucoma (EXG) and primary open-angle glaucoma (POAG). Methods: We prospectively investigated the preoperative features of 100 consecutive patients undergoing filtration surgery for either EXG, or POAG. We compared 74 patients with EXG and 26 with POAG. Results: EXG patients were older (68.2 vs 62.4 years; p∞0.05) and more often from the countryside (73%). Both glaucomas showed a preponderance for males, similar frequencies of positive family history and systemic disorders, with the exception of diabetes which was more common in POAG (19.2% vs 5.4%). The first IOP measurement, before treatment, was significantly higher in EXG (40.4 mm Hg) compared with POAG (33.9 mm Hg). Despite a shorter duration of medical therapy (25 vs 65 months) and more topical drugs EXG patients exhibited higher mean preoperative IOP (36 vs 27.8 mm Hg for POAG; p∞0.05). EXG patients had significantly worse visual acuity than POAG (0.4 vs 0.6; p∞0.05) and worse compliance to medical therapy (48%) compared to POAG (33%). Conclusion: Significant differences in preoperative features distinguish EXG from POAG.

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Pseudoexfoliation glaucoma in Greece

Cited by 39 publications

References 35 publications

Frequency of exfoliation syndrome in Greek cataract patients

Frequency of exfoliation syndrome in Greek cataract patients

Gonioscopic findings in Greek patients with exfoliation glaucoma

Preoperative features of patients with exfoliation glaucoma and primary open‐angle glaucoma. The AHEPA study

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