Pseudoephedrine-induced hypertensive emergency: Treatment with labetalol

Mariani, Peter J.

doi:10.1016/0735-6757(86)90159-2

Cited by 32 publications

(4 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The first choice in treatment is betablockers. It is known that hypertensive crises resulting from sympathetic hyperactivity because of pseudoephedrine and ephedrine overdose can be terminated within minutes with propranolol and labetolol administration 10,11 …”

Section: Discussionmentioning

confidence: 99%

“…It is known that hypertensive crises resulting from sympathetic hyperactivity because of pseudoephedrine and ephedrine overdose can be terminated within minutes with propranolol and labetolol administration. 10,11 Pseudoephedrine was blamed as the causative agent in 4 patients (3 hemorrhagic and 1 ischemic stroke) from a series of 22 cases associated with sympathomimetics used in the treatment of influenza infection. It is noteworthy that in these cases, the time between the use of sympathomimetic medication and the onset of a stroke clinic ranged from 30 minutes to 24 hours in 17 patients after the first dose.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Posterior Reversible Encephalopathy Syndrome Occurred During the Use of Pseudoephedrine: A Case Report

Gunduz¹

2022

Clin Neuropharm

View full text Add to dashboard Cite

Posterior reversible encephalopathy syndrome (PRES) is a syndrome that is manifested by a variety of clinical findings, like headache, seizure, loss of vision and change in consciousness, and characterized by bilateral vasogenic edema, which is usually located in the posterior part of the hemispheres, but sometimes located in atypical localization.Case Presentation: A 56-year-old man with no known systemic disease with generalized tonic clonic seizure was evaluated. He had oral paracetamol + pseudoephedrine HCl for runny nose, sore throat, and headache. After the second dosage, he had a seizure while sleeping. In flair sequence of magnetic resonance imaging, bilateral cortical and subcortical hyperintensities were observed in the posterior parts of the hemispheres and the cerebellar hemispheres, which demonstrated PRES. Conclusion:We presented a PRES case with seizures after using 2 doses of pseudoephedrine. In addition to hypertension, several factors have been blamed, such as eclampsia-preeclampsia, some immunosuppressive and chemotherapeutic drugs, some kidney diseases. Although the patient had no known risk factors for PRES, he was diagnosed with hypertension and diabetes mellitus during follow-up.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Posterior Reversible Encephalopathy Syndrome Occurred During the Use of Pseudoephedrine: A Case Report

Gunduz¹

2022

Clin Neuropharm

View full text Add to dashboard Cite

show abstract

“…In cases such as our patient, treatment is largely symptomatic because renal clearance is lost and removal by standard haemodialysis is modest. Pharmacological antagonism of alpha and beta adrenergic effects with drugs, such as labetalol and propranolol, is recommended where side‐effects are unacceptable, 6 , 7 particularly cardiovascular side‐effects.…”

Section: Discussionmentioning

confidence: 99%

Pseudoephedrine Toxicity in Renal Failure

Lyon

Turney

1996

Int J Clinical Practice

View full text Add to dashboard Cite

show abstract

“…The phenomenon of “unopposed α‐stimulation” has never been reported for patients with toxicity from the designer drugs outlined in the review and is a topic of controversy for patients with cocaine toxicity . Clinical evidence for safe use of β‐blockers in the treatment of stimulant toxicity exists with several studies and case reports . We believe that clinical evidence to not support their use is what is lacking.…”

mentioning

confidence: 91%