Pseudocyesis: A complication of antipsychotic-induced increased prolactin levels and weight gain

Grover, Sandeep; Sharma, Akhilesh; Ghormode, Deepak; Rajpal, Nikita

doi:10.4103/0976-500x.114610

Cited by 8 publications

(5 citation statements)

References 6 publications

(17 reference statements)

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“…Según Brockington, es frecuente que mujeres que no se encuentran en estado de gravidez, en algún momento crean que lo están sin que esto sea verdaderamente cierto (10) , la conceptualización de la Pseudociesis, de acuerdo con al DSM-V y al CIE-10, comprende la idea falsa o errónea de encontrarse en estado gestacional, y se vincula con la presencia de signos y síntomas del embarazo (11,12) , esto suele ir acompañado de distensión abdominal, alteraciones del ciclo menstrual, percepción de movimientos fetales, molestias digestivas y cambios en las mamas, lo que ha sido constatado en el caso presentado anteriormente. Además, la paciente no tenía control sobre las características físicas del embarazo, es decir, no se evidenció el consumo de algún fármaco o sustancia que provoque la producción de leche ni el aumento del tamaño abdominal (13) .…”

Section: Discussionunclassified

Pseudociesis. Reporte de caso

Maggi Cárdenas,

Vázquez Alcaraz,

Madelaire

et al. 2024

An. Fac. Cienc. Méd. (Asunción)

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Introducción: Según el DSM-V, la pseudociesis se incluye en la categoría "otros síntomas somáticos específicos y trastornos relacionados" y se define como la falsa creencia de estar embarazada que se asocia con signos objetivos y síntomas de embarazo. La confirmación de la pseudociesis se consigue con un resultado negativo de la gonadotropina coriónica humana beta en la sangre y/o la orina asociado a un hallazgo ecográfico negativo. Materiales y métodos: se presenta el caso de mujer con síntomas y signos de embarazo que corresponden a pseudociesis, la paciente siguió creyendo que estaba embarazada debido a sus síntomas, a pesar de que las pruebas de embarazo dieron negativo. Conclusión: La pseudociesis es una enfermedad poco frecuente que a menudo se asocia a otras comorbilidades psiquiátricas y diagnósticos diferenciales poco claros. Es necesario la realización de más estudios, incluyendo series de casos y revisiones sistemáticas para comprender mejor esta infrecuente condición y sus otras variantes.

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Section: Discussionunclassified

Pseudociesis. Reporte de caso

Maggi Cárdenas,

Vázquez Alcaraz,

Madelaire

et al. 2024

An. Fac. Cienc. Méd. (Asunción)

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“…However, rare cases in premenarchal and postmenopausal women have also been reported in literature [4,7,10]. Previous studies also suggest that cases of pseudocyesis are more prevalent in developing countries or underdeveloped countries as compared to developed nations [8,21]. The etiology of pseudocyesis remains obscure [11].…”

Section: Discussionmentioning

confidence: 99%

“…al, in which remission of pseudocyesis symptoms occurred after the initiation of hormone therapy with thyroxine in a woman with elevated TSH level, is an example that demonstrates the possible association of endocrinopathies with the development of pseudocyesis. Some studies also considered pseudocyesis as possibly due to an antipsychotic-associated hyperprolactinemia and metabolic syndrome [8,9]. Psychological factors such as intense desire for pregnancy [1], psychological stress-induced hyperprolactinemia [23,24], grief reaction following tubal ligation, or hysterectomy were also found to be contributing factors to pseudocyesis.…”

Section: Discussionmentioning

confidence: 99%

A Comprehensive Review of Pseudocyesis and its Associated Psychiatric Disorders

Harry,

Folorunsho,

Anona

et al. 2024

J. Adv. Med. Med. Res.

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Background: Pseudocyesis (or pseudocyesis vera) also known as “phantom pregnancy” was previously described according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) as a false belief of being pregnant that is associated with objective signs and reported symptoms of pregnancy. The exact etiology and management of this rare disorder are not known but certain factors have been associated with this including the presence of certain psychiatric conditions. Objective: This study aims to provide a better understanding of the factors associated with pseudocyesis including psychiatric disorders and available treatment modalities. Materials and Methods: A comprehensive review of literature on pseudocyesis in humans and its association with various psychiatric conditions. Available articles published from 1970 to January 2021 were included. Using the following keywords- “pseudocyesis, false pregnancy, psychiatric disorders, schizophrenia, phantom pregnancy”, relevant articles from Google Scholar, PubMed, ScienceDirect, and Web of Science were searched and reviewed. Our initial search yielded 871 articles, out of which 14 were deemed fully eligible. Results: According to our review, it has been found that various social and cultural factors such as strong cultural views on the need for childbearing as prerequisite for womanhood have led to the manifestation of this condition. The etiology of pseudocyesis is associated with various psychological and endocrine disturbances sometimes mediated by psychosomatic disorders. Conclusion: Pseudocyesis could be associated with psychiatric conditions such as major depression, schizophrenia, bipolar disorder, hypomania, and post-traumatic stress disorder. The treatment options may vary according to the presence of co-morbidities in different patients. Adopting a multidisciplinary approach encompassing gynecologists, psychologists and psychiatrists, is important in providing holistic care for this group of patients.

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“…2 Pseudocyesis is a multifactorial disorder and its evolution is influenced by many different elements such as neuroendocrine, social, psychodynamic, and cultural issues. 3 Few case reports have also mentioned pseudocyesis in relation to antipsychotic-associated hyperprolactinemia [4][5][6][7] and metabolic syndrome. 8 Although in cases of pseudocyesis, single fetus is most commonly reported but often patients may report more than one.…”

Section: Introductionmentioning

confidence: 99%

Pseudocyesis Leading to Folie-à-Deux

Nagdive

Bhainsora

Fernandes

et al. 2021

JNRP

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Pseudocyesis or false belief of pregnancy is the emergence of classical manifestations of pregnancy—nausea, breast enlargement and pigmentation, abdominal distention, amenorrhea, and labor pains—in a nonpregnant woman. It is a multifactorial disease and its development is influenced by many different elements such as neuroendocrine, social, psychodynamic, and cultural issues. “Folie-à-deux,” is shared psychotic disorder, describes a syndrome in which delusion is transferred to another person who is more susceptible. Both individuals are closely related or know each other for a long time and typically live together in relative social isolation. In its commonest form, the individual who first develops the delusion (the primary case) is often chronically ill and typically is the dominant member in a close relationship with a more suggestible person (the secondary case) who also develops the delusion. Treatment options should also be kept in mind as antipsychotics themselves can increase prolactin levels and can lead to amenorrhoea and galactorrhea and can further strengthen patient’s belief about her pregnancy. This case highlights that the most important therapeutic step in the treatment of folie-à-deux is separation of the inducer and the induced. Here we describe a case of folie-à-deux of a married couple in which the female had delusional pregnancy while the husband shared and supported her delusion against substantial medical evidence.

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Pseudocyesis: A complication of antipsychotic-induced increased prolactin levels and weight gain

Cited by 8 publications

References 6 publications

Pseudociesis. Reporte de caso

Pseudociesis. Reporte de caso

A Comprehensive Review of Pseudocyesis and its Associated Psychiatric Disorders

Pseudocyesis Leading to Folie-à-Deux

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