Pseudocarcinomatous Sweet syndrome

Lukach, Alexis J.; Han, Joohee; Gardeen, Samantha J.; English, Joseph C.; Rosenman, Karla; Speetzen, Larisa S.; Werling, Robert

doi:10.1016/j.jdcr.2022.06.010

Cited by 1 publication

(2 citation statements)

References 7 publications

(12 reference statements)

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“…In the present case, the histopathological findings of the nasal lesion suggested an epithelial response with proliferation of squamous cells toward cornifi- (2,12,13). Although Sweet syndrome is often seen in cases of hematologic malignancies, such as AML, PCH is a very rare dermal histopathological finding in AML (2,12). In the present case, there was no histopathological evidence to suggest Sweet syndrome in the specimens obtained by nasal debridement.…”

Section: Discussioncontrasting

confidence: 49%

“…Grunwald et al reported two types of PCH in the skin: an epithelial response with proliferation of basaloid cells and an epithelial response with proliferation of squamous cells toward cornification (4). In the present case, the histopathological findings of the nasal lesion suggested an epithelial response with proliferation of squamous cells toward cornifi- (2,12,13). Although Sweet syndrome is often seen in cases of hematologic malignancies, such as AML, PCH is a very rare dermal histopathological finding in AML (2,12).…”

Section: Discussionmentioning

confidence: 45%

See 1 more Smart Citation

Pseudocarcinomatous Hyperplasia of the Nose and Necrotic Tracheitis Associated with Acute Myeloid Leukemia

Kajikawa,

Murakami,

Takami

et al. 2024

Intern. Med.

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A 29-year-old woman who had been diagnosed with acute myeloid leukemia presented with persistent grade-4 febrile neutropenia (FN) after initial chemotherapy with idarubicin and cytarabine. Despite intensive treatment, FN persisted. Subsequently, her nose became reddish and swollen, obstructing the nasal cavities. Computed tomography revealed swelling of the nostrils and an irregular tracheal surface. Debridement of the nasal lesion and a bronchoscopic biopsy of the tracheal lesion were also performed. A histopathological examination revealed pseudocarcinomatous hyperplasia (PCH) of the nose and necrotizing tracheitis. Both nasal PCH and necrotizing tracheitis ameliorated when the patient recovered from leukocytopenia.

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