Pseudoangiomatous Stromal Hyperplasia of Breast in an Adolescent: A Case Report and Review of the Literature

Köksal, Hande; Kara, Buket; Karanis, Meryem İlkay Eren; Şen, Sevil; Köksal, Yavuz

doi:10.1016/j.jpag.2020.12.005

Cited by 6 publications

(11 citation statements)

References 12 publications

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“… 5 In Koksal et al’s study, a 13‐year‐old girl was reported, with a giant mass in her left breast. 6 In another report by Willy et al, PASH presented as extreme gigantomastia in a 29‐year‐old woman. 7 PASH tumors rarely mimic clinical presentations of malignant breast entities.…”

Section: Discussionmentioning

confidence: 94%

“…Abdelrahman et al reported 35 cm breast enlargement in a 13‐year‐old female which was later diagnosed as PASH tumor 5 . In Koksal et al’s study, a 13‐year‐old girl was reported, with a giant mass in her left breast 6 . In another report by Willy et al, PASH presented as extreme gigantomastia in a 29‐year‐old woman 7 .…”

Section: Discussionmentioning

confidence: 97%

“… 4 Koksal et al removed the lesion surgically and in six‐month follow‐up, no recurrence happened. 6 Raj et al preferred surgery, especially in patients with large tumors and higher risks for breast malignancies. 8 Raza et al treated their patient conservatively.…”

Section: Discussionmentioning

confidence: 99%

“…In Yoon et al’s study, the preferred management of large tumors (>3 cm) or progressively growing tumors was surgical removal or close observation of lesions and deciding accordingly 4 . Koksal et al removed the lesion surgically and in six‐month follow‐up, no recurrence happened 6 . Raj et al preferred surgery, especially in patients with large tumors and higher risks for breast malignancies 8 .…”

Section: Discussionmentioning

confidence: 99%

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Pseudoangiomatous stromal hyperplasia of the breast: A case report

Tahmasebi

Zadeh

Zangouri

et al. 2022

Clinical Case Reports

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Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Pseudoangiomatous stromal hyperplasia of the breast: A case report

Tahmasebi

Zadeh

Zangouri

et al. 2022

Clinical Case Reports

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“…Although PASH has previously been defined as a lesion seen in premenopausal women, it is now known that it can be seen in males and females aged 12–75 years. [ 1 , 4 ] These lesions can be detected in premenopausal women taking oral contraceptives or postmenopausal women taking hormone replacement treatment (HRT), transsexual males or those with gynecomastia taking exogenous hormones, and children and/or adolescents with other disorders such as neurofibromatosis type 1, morbid obesity, or precocious puberty. [ 4 - 9 ] This has emphasized the association of the lesion with hormonal factors.…”

mentioning

confidence: 99%

The relationship of PASH (pseudoangiomatous stromal hyperplasia)-like appearance in invasive breast carcinomas with PASH areas in non-tumoral breast parenchyma as well as on axillary lymph node involvement

Sigirci¹

2022

Sisli Etfal

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Objectives: The aim of this study were to determine the relationship of pseudoangiomatous stromal hyperplasia (PASH)-like appearance in invasive breast carcinomas (IBCs) with PASH foci in the non-tumoral breast parenchyma as well as axillary lymph node involvement. Methods: In this study, 200 consecutive cases with IBC were re-examined. Cases with and without PASH-like appearance in IBC were determined. Each case was assessed regarding the presence of accompanying PASH foci (CD34+, CD31-) in the non-tumoral areas in addition to other clinicopathological parameters. Results: PASH-like appearance within the IBC was present in 22 of the 200 cases (11%) and absent in 178 (89%). The presence of PASH foci in the non-tumoral breast parenchyma was significantly more common in IBC with PASH-like appearance compared to the group without such areas. However, there was no significant difference between the groups regarding other clinicopathological parameters (age, tumor size, nuclear and histological grade, Estrogen receptor/Progesterone receptor status, HER2 status, and Ki-67 proliferation index), lymphovascular invasion (LVI), and axillary lymph node involvement. There was no significant difference between the two groups regarding the histopathological findings observed in the non-tumoral areas. Conclusion: PASH-like appearance within IBC was found to be associated with higher rate of PASH foci in the non-tumoral breast parenchyma. However, such cases do not show a difference as regards LVI and axillary lymph node metastasis.

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Pseudoangiomatous stromal hyperplasia of the breast, imaging and clinical perspective: A review

Alikhassi

Skarpathiotakis

et al. 2023

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Pseudoangiomatous stromal hyperplasia (PASH) is a benign breast pathology, which most commonly presents incidentally along with other breast pathologies. The etiology and pathogenesis of PASH are still unknown; however, there is some evidence suggesting PASH is hormone dependent. The clinical history, presentation, and imaging appearance of PASH are variable. Clinically, PASH has a wide spectrum of presentations, from being silent to gigantomastia. On imaging, PASH demonstrates various benign to suspicious features. Here we summarize PASH’s clinical presentation, histopathology, imaging features, and management.

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Pseudoangiomatous Stromal Hyperplasia of Breast in an Adolescent: A Case Report and Review of the Literature

Cited by 6 publications

References 12 publications

Pseudoangiomatous stromal hyperplasia of the breast: A case report

Pseudoangiomatous stromal hyperplasia of the breast: A case report

The relationship of PASH (pseudoangiomatous stromal hyperplasia)-like appearance in invasive breast carcinomas with PASH areas in non-tumoral breast parenchyma as well as on axillary lymph node involvement

Pseudoangiomatous stromal hyperplasia of the breast, imaging and clinical perspective: A review

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