PSAT1 mediated EMT of colorectal cancer cells by regulating Pl3K/AKT signaling pathway
Mingjin Wang,
Houshun Zhang,
Zhiyuan Lu
et al.
Abstract:Background:
The metastasis of colorectal cancer (CRC) is one of the significant barriers impeding its treated consequence and bring about high mortality, less surgical resection rate and poor prognosis of CRC patients. PSAT1 is an enzyme involved in serine biosynthesis. The studies showed that PSAT1 plays the part of a crucial character in the regulation of tumor metastasis. And Epithelial-Mesenchymal Transition (EMT) is a process of cell reprogramming in which epithelialcells obtain mesenchymal phe… Show more
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