Psammomatous cerebral intra‐ventricular meningioma in a bull

Eröuküuz, Y.; Metin, Nursal; Öouzer, H.; Yaman, Ihsan; Clevik, A.

doi:10.1111/j.1751-0813.1999.tb10317.x

Cited by 4 publications

(4 citation statements)

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“…This trend has been described in the literature where the majority of cattle with meningiomas were ≤2 years of age. 17,30 The main clinical manifestations of the intracranial neoplasms in the present study were altered mental stage, central vestibular dysfunction, and cerebellar incoordination. These were nonspecific signs and likely related to the location of the mass lesion and the associated increased intracranial pressure.…”

Section: Discussionmentioning

confidence: 53%

“…47 However, benign meningiomas, diagnosed only in 20% of the cases in this report, occurred less frequently than has been reported in humans (80%) 39 and in dogs (around 50%). 47 Infrequent cases of meningioma have been described in cattle, 1,13,17,30,48 and apart from an anaplastic meningioma, 48 none of the meningeal subtypes encountered here have been reported before. The majority has been described as the fibroblastic subtype and a link with bovine papillomavirus infection has been shown experimentally.…”

Section: Discussionmentioning

confidence: 63%

“…This is in accordance with previous reports on 4 out of 5 bovine meningiomas that were seen at the level of the cerebrum. 17,30 The metastatic carcinomas infiltrated the lateral medulla at the level of the pons in all cases and the ventral midbrain and the subarachnoid space each in one of these cases. Three case reports on metastasizing squamous cell carcinomas in cattle found a similar involvement of the lateral brainstem and ventral midbrain.…”

Section: Discussionmentioning

confidence: 93%

“…This trend has been described in the literature where the majority of cattle with meningiomas were ≤2 years of age. 17 , 30…”

Section: Discussionmentioning

confidence: 99%

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Bovine intracranial neoplasia: A retrospective case series

Jahns

McElroy²

2022

Vet Pathol

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This case series describes the clinical and pathological findings of intracranial neoplasms in cattle, a rare entity. Data and archived tissues from 24 intracranial tumors were reviewed and investigated by immunohistochemistry for S100, glial fibrillary acidic protein, synaptophysin, pancytokeratin, vimentin, neuron-specific enolase, oligodendrocyte transcription factor 2, and isocitrate dehydrogenase 1. Ages of affected cattle ranged from 6 months to 14 years (5.7 ± 3.6 years; mean ± SD). Predominant clinical signs were altered mental state, central vestibular dysfunction, and cerebellar incoordination. Twelve gliomas, all high grade, were the most common tumors observed: oligodendrogliomas (n = 6), astrocytomas (n = 4), and undefined gliomas (n = 2). The oligodendrogliomas were located in the brainstem and extended into the ventricles, whereas all astrocytomas were located in the forebrain. Isocitrate dehydrogenase 1 gene mutation as described in humans was not detected. The 5 meningiomas exhibited microcystic, chordoid, atypical, papillary, and anaplastic subtypes. Metastatic carcinomas (n = 4) were the only secondary tumor type present, and these were located at the level of the medulla with infiltration of cranial nerves and in one case leptomeningeal carcinomatosis. In addition, 2 medulloblastomas and 1 choroid plexus carcinoma were diagnosed. Immunohistochemistry for vimentin and pancytokeratin was particularly useful to distinguish meningiomas and choroid plexus carcinoma (positive for vimentin only) from mestastatic carcinomas (positive for cytokeratin only) as all showed a papillary growth pattern. Overall, the morphological features were comparable with other species and the human and canine classifications could be applied.

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Section: Discussionmentioning

confidence: 53%