Ps-C33-2: Hypertension, Obstructive Sleep Apnea and Hyperaldosteronism: A Bidirectional Mendelian Randomization Study

Abstract

Background:The aim was to conduct a comparative assessment of the circadian rhythm (CR) abnormalities and blood pressure (BP) levels between pseudo-and true resistant hypertension (RH) in obesity. Methods:The study included 302 patients with uncontrolled hypertension and obesity. Initial treatment efficacy was assessed 3 months after dual therapy was administered. Those patients who did not reach target BP in dual therapy were transferred to triple therapy. Among patients who received triple therapy, 69 people did not reach target BP. All patients were additionally examined 6 months after the therapy initiation.