Ps-Bpb04-6: Proof of Biological Activity and Exploration of Early Signaling Events of Angiotensin-(1–5)

Abstract

Conclusion:This study provides evidence that Ang-(1-5) is an endogenous AT 2 R agonist with high efficacy towards the AT 2 R. The early signaling phosphorylation pattern resembles those of other protective RAS agonists, such as C21 and Ang-(1-7).