Pruritus Intensity Scales across Europe: a prospective validation study

Storck, Michael; Sandmann, Sarah; Bruland, Philipp; Pereira, Manuel P.; Steinke, Sabine; Riepe, Claudia; Soto-Rey, Iñaki; Garcovich, Simone; Augustin, Matthias; Blome, Christine; Bobko, S.; Legat, Franz J.; Потекаев, Н. Н.; Lvov, A. N.; Miséry, Laurent; Weger, Wolfgang; Reich, Adam; Şavk, Ekin; Streit, Markus; Serra‐Baldrich, E.; Szepietowski, Jacek C.; Dugas, Martin; Ständer, Sonja; Zeidler, Claudia

doi:10.1111/jdv.17111

Cited by 31 publications

(33 citation statements)

References 26 publications

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“…A number of questionnaires evaluating itch severity have been developed so far. [5][6][7] Four-item itch questionnaire mainly focuses on the physical features of pruritus. Its significant correlation with mental parameters such as quality of life impairment, depression level and stress severity was reported.…”

Section: Discussionmentioning

confidence: 99%

Haemorrhagic dots as a dermoscopic marker of itch severity in psoriasis

2021

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The quality of life is commonly reduced in patients with psoriasis not only because of aesthetic issues and troublesome treatment but also because of itch. 1,2 Pruritus occurs in 60-90% of psoriatic patients and may be caused by immune, neurological or vascular mechanisms. 3,4 The therapeutic approach should include itch management adjusted to pruritus severity. 1 Multiple questionnaires are used to evaluate itch severity. However, their use may be time-consuming. 5,6 Furthermore, the patients' perception of pruritus-related impact on the quality of life, sleep and psychosomatic reactions may differ depending on the patients' current mood, environmental factors or stress. 7 Therefore, the need of using objective methods of the evaluation of itch severity was emphasised. 7 Patients experiencing itch rub or scratch the skin which may result in developing excoriations in severe cases. However, most commonly chronic, the repeated traumatisation of the skin results in the occurrence of the Auspitz sign and the Koebner phenomenon, which provokes plaques to be more persistent and to renew frequently. 3 The Auspitz sign observed in psoriasis cases was documented in dermoscopic studies as haemorrhagic dots on the skin or in the scale. 8 The aim of this study was to evaluate if the presence of haemorrhagic dots under dermoscopy corresponds with the severity of itch.

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Section: Discussionmentioning

confidence: 99%

Haemorrhagic dots as a dermoscopic marker of itch severity in psoriasis

2021

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“…Survey data included demographics, clinical diagnoses, itch intensity (numerical rating scale, 0 to 10), itch characteristics, and the ItchyQoL survey-a self-report survey that measures 21 items and scores QoL into 3 subcategories: symptoms, functioning, and emotions. 4,5 The average response rate for all items was 89.4%. Itch diagnoses were divided into 7 categories: inflammatory, idiopathic, neuropathic, systemic, localized, psychogenic, and ''other.''…”

Section: The Association Of Chronic Pruritus With Patients' Quality O...mentioning

confidence: 99%

The association of chronic pruritus with patients' quality of life: A cross-sectional study

Lipman

Yap

Rosen

et al. 2022

Journal of the American Academy of Dermatology

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“…The VRS includes five itching severities: no, low, moderate, severe and extremely severe [ 30 ]. A study recommended that the cut-off values for both the VAS and the NRS are converted into VRS values of 3–7–9 (i.e.…”

Section: Diagnosis Of Ckd-apmentioning

confidence: 99%

“…The 24-h Worst Itching Intensity NRS (WI-NRS) is a validated version of the NRS in which patients grade the overall severity of the worst level of their itching in the previous 24 h. The European Network on Assessment of Severity and Burden of Pruritus recently has validated both the 24-h WI-VAS/NRS/VRS and the 24-h average itching intensity VAS/NRS/VRS in different languages and in different dermatoses [ 30 ] ( Figure 1 ).…”

Section: Diagnosis Of Ckd-apmentioning

confidence: 99%

Do you feel itchy? A guide towards diagnosis and measurement of chronic kidney disease-associated pruritus in dialysis patients

Manenti

Leuci

2021

Clinical Kidney Journal

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Chronic kidney disease-associated pruritus (CKD-aP) is a potentially distressing condition that affects a significant proportion of patients with end-stage kidney disease undergoing dialysis. CKD-aP may lead to worsening of patients’ physical and mental health-related quality of life (HRQoL) and has also been linked with worse clinical outcomes, including increased mortality. Despite these detrimental effects, evidence from real-world studies shows that CKD-aP still remains overlooked by nephrologists and underreported by patients in clinical practice. Itch is subjective and therefore its diagnosis is often dependent on patients reporting this symptom. There is an opportunity to reduce the burden of CKD-aP on dialysis patients by increasing awareness about this condition and the availability of effective treatments. It is particularly important that nephrologists and other healthcare providers routinely ask their patients if they are experiencing itch. The differential diagnosis of CKD-aP requires a step-by-step identification and exclusion of possible alternative or concomitant causes of itch. Several simple validated self-reported assessment scales are available to evaluate the presence and severity of itch in a time-efficient manner, making them suitable for use in everyday clinical practice. The impact of CKD-aP on haemodialysis patients’ HRQoL should also be assessed on a regular basis. This review provides a comprehensive overview of the differential diagnosis of CKD-aP and the diagnostic tools that are available to identify itch and quantify its severity and impact on patient HRQoL. A suggested algorithm to guide the screening, diagnosis and assessment of CKD-aP among dialysis patients in real-world practice is provided.

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Pruritus Intensity Scales across Europe: a prospective validation study

Cited by 31 publications

References 26 publications

Haemorrhagic dots as a dermoscopic marker of itch severity in psoriasis

Haemorrhagic dots as a dermoscopic marker of itch severity in psoriasis

The association of chronic pruritus with patients' quality of life: A cross-sectional study

Do you feel itchy? A guide towards diagnosis and measurement of chronic kidney disease-associated pruritus in dialysis patients

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