Pruritus in Systemic Diseases: A Review of Etiological Factors and New Treatment Modalities

Tarikci, Nagihan; Kocatürk, Emek; Güngör, Şükrü; Topal, İlteriş Oğuz; Can, Pelin Ülkümen; Singer, Ralfi

doi:10.1155/2015/803752

Cited by 44 publications

(48 citation statements)

References 74 publications

(92 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…O prurido é definido como o desejo de se escoriar ou arranhar, decorrente de uma sensação de irritação incômoda na pele (Tarikci et al 2015). Assim, as doenças pruriginosas causam desconforto, afetam a aparência, predispõem a pele a infecções secundárias ou miíases e interferem no ganho de peso e na reprodução animal (Radostits et al 2007).…”

Section: Introductionunclassified

Surtos de fotossensibilização e dermatite alérgica em ruminantes e equídeos no Nordeste do Brasil

et al. 2018

View full text Add to dashboard Cite

RESUMO.-O presente estudo foi conduzido com o objetivo de determinar as causas de fotossensibilização em ruminantes e equídeos no Nordeste do Brasil, através da revisão dos laudos de exames arquivados no Laboratório de Patologia Veterinária da Universidade Federal da Paraíba. Durante os quatro anos do estudo foram diagnosticados 22 surtos de fotossensibilização, incluindo 11 surtos de fotossensibilização primária e oito surtos de fotossensibilização hepatógena. A intoxicação por Froelichia humboldtiana foi a principal causa de fotossensibilização e a única causa de fotossensibilização primária. As espécies mais gravemente afetadas por fotossensibilização primária foram os asininos, caprinos, bovinos e ovinos, mas os equinos e mulas também são afetados. A intoxicação por Brachiaria decumbens foi a principal causa de fotossensibilização hepatógena e afetou apenas os ovinos e bovinos. Outras plantas associadas com fotossensibilização The study was conducted to determine the causes of photosensitization in ruminants and equidae in northeastern Brazil through a review of the files at the Laboratório de Patologia Veterinária of Universidade Federal da Paraíba. During four years of the study 22 outbreaks of photosensitization were diagnosed, including 11 outbreaks of primary photosensitization and eight outbreaks of hepatogenous photosensitization. Poisoning by Froelichia humboldtiana was the main cause of photosensitization, and the only cause of primary photosensitization. The most severely affected animals by primary photosensitization are donkeys, goats, cattle and sheep, but horses and mules may also be affected. Poisoning by Brachiaria decumbens was the main cause of hepatogenous photosensitization, and affected only sheep and cattle. Other plants associated with hepatogenous photosensitization in cattle include Enterolobium contortisiliquum and Lantana camara. Allergic dermatitis was diagnosed in two flocks of sheep and in a horse. The animals had chronic lesions characterized by areas of alopecia, crusts and hyperpigmentation on the head, around the eyes (sheep) and at the legs (horse). Itching was the main clinical sign in cases of primary photosensitization and insect hypersensitivity.

show abstract

Section: Introductionunclassified

Surtos de fotossensibilização e dermatite alérgica em ruminantes e equídeos no Nordeste do Brasil

et al. 2018

View full text Add to dashboard Cite

show abstract

“…

ated with a desire to scratch [1] . Just like skin pruritus, its etiology may be of dermatological or non-dermatological origin.

…”

mentioning

confidence: 99%

Scalp Itch: A Systematic Review

Vázquez-Herrera

Sharma

Aleid

et al. 2017

Skin Appendage Disord

View full text Add to dashboard Cite

ated with a desire to scratch [1] . Just like skin pruritus, its etiology may be of dermatological or non-dermatological origin. It is common for the dermatologist to encounter patients with no evident cause of scalp pruritus, making it a distressing situation for both the clinician and the patient. The aim of this paper is to review the clinical signs of the most common causes of scalp itch and other less common causes that must be considered in a systematic approach to scalp pruritus. Materials and MethodsWe performed a MEDLINE search through PubMed (1975PubMed ( -2017, using the terms scalp itch and scalp pruritus and included clinical trials, review articles, case series, and case reports to search for the causes of scalp itch. PathophysiologyAlthough various pathogenic etiologies contribute to scalp pruritus, the scalp itself has distinct neuroanatomy and vasculature, specific neuromediators and corresponding receptors, as well as the presence of scalp sebum and microflora, which are all properties that may explain its tendency to be implicated in patients who complain of itch. Keywords Scalp · Itch · Pruritus · Seborrheic dermatitis · Contact dermatitis · Anxiety · Lichen planopilaris · Lice · Pediculosis · Psoriasis · Trichoscopy AbstractScalp itch is a frequent complaint in the dermatological setting. It is common for the dermatologist to encounter patients with no evident cause of scalp pruritus, making it a distressing situation for both the clinician and the patient. The aim of this paper is to propose a systematic approach to scalp itch, which classifies scalp pruritus into two types: (1) with or (2) without dermatological lesions, and presence or absence of hair loss. Also, it is important to think first about the most common causes and then rule out other, less common etiologies. The acronym SCALLP and the five steps for scalp evaluation (listen, look, touch, magnify, and sample) are useful tools to keep in mind for an assertive approach in these patients.

show abstract

“…GCP in patients with diabetes mellitus reveals no significant higher incidence rates than non‐diabetics; pruritus itself, however, could be the primary symptom of diabetes in such cases . It seems that the truncal pruritus of unknown origin is more common in diabetics . It is believed that diabetic polyneuropathy metabolic abnormalities, autonomic nervous system dysfunctions, and anhydrosis could all be the possible etiologies of CP among patients with DM .…”

Section: Discussionmentioning

confidence: 96%

“…The dry skin initiated by hypothyroidism could have probably caused GCP. This itching responds to emollients and thyroid hormone replacement …”

Section: Discussionmentioning

confidence: 99%

Chronic generalized pruritus without primary skin lesions: a longitudinal prospective observational study

et al. 2018

View full text Add to dashboard Cite

Pruritus is among the most common complaints in the field of dermatology. It is also a disturbing symptom of many systemic disorders. Chronic pruritus (CP) refers to the cases of the symptom which last longer than 6 weeks. We conducted a prospective analysis of patients with generalized pruritus without primary skin lesions. All patients underwent primary evaluations and then were followed from 12 to 18 months for further evaluations. Of the 5,127 patients referred to our dermatology clinic, 49 patients with generalized pruritus without primary skin lesions were evaluated. Most of the patients (44%) were in the age group of 40-60 years and female (58%). The duration of pruritus was 37.04 ± 30.4 weeks. Fifty percent of the patients with generalized pruritus had a systemic cause of pruritus. The most common underlying diseases were thyroid disorders (16.67%), diabetes mellitus (12.5%), and malignancy (8.33%). There were no significant statistical differences among the patients in terms of their age, gender, and disease duration with the underlying diseases (P = 0.47, P = 0.99, P = 0.816, respectively). However, the average age of the onset of pruritus was 12 years earlier in the women regardless of the underlying diseases (P = 0.011). Based on the findings of the study, we recommend considering endocrine disorders and malignancies as the most common underlying diseases leading to chronic pruritus without primary skin lesions.

show abstract

Pruritus in Systemic Diseases: A Review of Etiological Factors and New Treatment Modalities

Cited by 44 publications

References 74 publications

Surtos de fotossensibilização e dermatite alérgica em ruminantes e equídeos no Nordeste do Brasil

Surtos de fotossensibilização e dermatite alérgica em ruminantes e equídeos no Nordeste do Brasil

Scalp Itch: A Systematic Review

Chronic generalized pruritus without primary skin lesions: a longitudinal prospective observational study

Contact Info

Product

Resources

About