Prurigo pigmentosa: An institutional retrospective study of 24 patients

Seol, Jung Eun; Cho, Gyeong Je; Park, So Hee; Kim, Hyojin

doi:10.1111/ajd.13435

Cited by 3 publications

(3 citation statements)

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“…The resolving lesions were characterized by crusted papules and the late lesions were characterized by reticulate hyperpigmentation. 2 , 9 , 10 Our study showed the lesions of PP could be focal or multifocal, but most of them were symmetrical. Lesions of different stages often presented at the same time in the same patient, which revealed how the lesions develop.…”

Section: Discussionmentioning

confidence: 62%

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Dermoscopy and reflection confocal microscope features of pigmented prurigo

Wang

Xiao-fang

Xiangfen

et al. 2022

Skin Research and Technology

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Background: Pigmented prurigo (PP) is a chronic and recurrent inflammatory skin disease. PP is not common clinically, but it is easily misdiagnosed because of its diversified clinical manifestations in different stages. Materials and methods:We retrospectively analyzed the clinical, histopathological, dermoscopy, and reflectance confocal microscopy (RCM) features of 20 patients diagnosed as PP. Results:The female predominance ratio was revealed with male to female of 1:4.Seven female patients were on a diet (without staple food) and one patient had a history of diabetes. Eight cases were suffered in spring, six cases in winter, three cases in summer, and three cases in autumn. Multiple sites were involved in 13 cases.Four patients had urticarial papules and plaques. Nineteen patients had erythematous papules with reticular distribution, of which 14 cases accompanied reticulate hyperpigmentation, four cases with papulovesicle, and two cases accompanied with pustules. One patient only showed reticulate hyperpigmentation. In the early lesions, dermatoscopy showed pink oval lesions, punctate or linear vessels, and pale yellow rings around the skin lesions. RCM is characterized by spongiosis, spongy vesicle, neutrophils scattered in the epidermis, which was consistent with epidermis spongiosis, neutrophils infiltrating into the upper epidermis and necrotic keratinocytes in histopathology. In the fully developed lesions, dermatoscopy showed pink lesions with brown pigment granules in the center and linear vessels in the edge. RCM showed that demarcation of epidermis and dermis is not clear, and inflammatory cells can be seen in the upper dermis and histopathologically lesions assumed a patchy lichenoid pattern, and the inflammatory cells infiltrating the dermis were dominated by lymphocytes.In the late lesions, dermatoscopy showed grainy grayish-brown or yellowish-brown pigmentation surrounding the hair follicle merging with each other. RCM showed that pigment granules were increased on the ring of basal cells, inflammatory cells were sparsely infiltrated in the dermal papilla and superficial layer, and epidermis slightlyThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Section: Discussionmentioning

confidence: 62%

“…The fully developed lesions were characterized by papules, papulovesicles forming reticular distribution. The resolving lesions were characterized by crusted papules and the late lesions were characterized by reticulate hyperpigmentation 2,9,10. Our study showed the lesions of PP could be focal or multifocal, but most of them were symmetrical.…”

mentioning

confidence: 63%