ProxyTyper: Generation of Proxy Panels for Privacy-aware Outsourcing of Genotype Imputation
Degui Zhi,
Xiaoqian Jiang,
Arif Harmanci
Abstract:One of the major challenges in genomic data sharing is protecting the privacy of participants. Numerous studies demonstrated that genetic data and related summary statistics can be used for identifying individuals. These studies led to a strong chilling effect on researchers that hindered collaborative data sharing. Consequently, population-level genetic databases are often siloed in central repositories with complex and burdensome data usage agreements. While cryptographic methods that are provably secure hav… Show more
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