Proximity to oil refineries and risk of bladder cancer: A population-based analysis.

Abstract

4538 Background: Exposure to aromatic amines is a risk factor for bladder cancer. Incidence rates according to proximity to oil refineries are largely unknown. We sought to determine proximity of oil refineries and bladder cancer incidence in the State of Texas which is home to the largest number of oil refineries in the United States. Methods: We used the Texas Cancer Registry database to identify patients diagnosed with bladder cancer from January 1, 2001 to December 31, 2014. The U.S. census data from 2010 was used to ascertain overall population size, age and sex distributions. Heat maps of the 28 active oil refineries in Texas were developed. Incidence of bladder cancer were compared according to proximity ( < 10 vs. ≥ 10 miles) to an oil refinery. Risk ratios were adjusted using a Poisson regression model. Results: A total of 45,517 incident bladder cancer cases were identified of which 5,501 cases were within 10 miles of an oil refinery. In adjusted analyses, bladder cancer risk was significantly greater among males vs. females (Relative Risk (RR) 3.41, 95% Confidence Interval (CI), 3.33-3.50), and greater among people living within 10 miles from an oil refinery than those living outside a 10-mile radius from an oil refinery (RR 1.19, 95% CI, 1.08-1.31). Conclusions: People living within 10 miles from oil refineries were at greater risk for bladder cancer. Further research into exposure to oil refineries and bladder cancer incidence is warranted.

Biosorption behavior of acid orange 7 dye onto Cucumis sativus peel biochar and its effect on growth of Triticum aestivum

“…Dafashy et al reported development of bladder cancer due to the long-term exposure of animals with aromatic amines. 5 The release of untreated dye containing effluent into water bodies degrade water quality by enhancing chemical and biochemical oxygen demand, inhibiting photosynthesis, depletion of oxygen in water bodies, show mutagenic or teratogenic effects on aquatic flora and fauna through entering in the food chain. 6 Aquatic organisms and fishes are rich source of proteins, dyes indigested by them can be metabolized into harmful intermediates which show adverse effects on fishes' health.…”

“…The carcinogenic aromatic amines such as benzidine and its derivatives are used for azo dye production. Dafashy et al reported development of bladder cancer due to the long‐term exposure of animals with aromatic amines 5 . The release of untreated dye containing effluent into water bodies degrade water quality by enhancing chemical and biochemical oxygen demand, inhibiting photosynthesis, depletion of oxygen in water bodies, show mutagenic or teratogenic effects on aquatic flora and fauna through entering in the food chain 6 .…”