Interoperability of GOOSE messages is essential for the proper operation of protection schemes such as the parallel power transformer (PTRF) differential protection scheme, especially when using multivendor IEC 61850 devices. GOOSE messages allow for fast and reliable communication between intelligent electronic devices (IEDs) and are based on Ethernet communication. To ensure the interoperability of GOOSE messages between multivendor devices, adherence to the IEC 61850 standard specifications is crucial. The standard defines the format and content of GOOSE messages, including the data object model, data types, and communication protocols. Third-party testing and certification programs can also ensure compliance with the standard and help guarantee interoperability between different vendors. Device conformance with these standards does not ensure interoperability when devices from various manufacturers are utilized. Interoperability is necessary between the relevant devices from various vendors to provide system power stability and protection. If multivendor device interoperability is achieved, power utilities will be able to utilize multivendor devices in substations. The study investigates and provides comprehensive methods for achieving IEC 61850 standard-based interoperability problems in parallel with PTRF’s current differential protection schemes between IEDs (SEL-487E and MiCOM-P645) produced by different vendors under fault conditions. In a lab-scale environment with RTDS for real-time simulation in Hardware-in-the-Loop (HIL), the designed technique is simulated and tested.