Providencia Rettgeri: An Unexpected Cause of Sepsis.

Abstract

Providencia rettgeri is a member of Enterobacteriacea that is known to cause urinary tract infection (UTI), septicemia, and wound infections, especially in immunocompromised patients and in those with indwelling urinary catheters. It is an uncommon cause of UTI and sepsis but should be suspected in patients with predisposing factors. The condition has high mortalty and warrants early recognition and treatment. We present here a case of UTI with sepsis by Providencia rettgeri in a young female during post partum period. She had recently delivered a male baby and was catheterized for 10 days. Patient received intravenous antibiotis and recovered completely. …………………………………………………………………………………………………….... Introduction:-The genus Providencia is a member of theEnterobacteriaceae family which commonly dwells in soil, water, and sewage [1]. Human isolates of Providencia species have been recovered from urine, throat, perineum, axilla, stool, blood and wound specimens. The organism is usually isolated from genitourinary and gastrointestinal sources (urine, faeces and perineum), causing diarrhoea and urogenital symptoms .Providencia rettgeri (P. rettgeri) is a motile, gram-negative rod shaped organism and a member of the Enterobacteriaceaefamily [1]. It is inherently resistant to many antibiotics and thus early identification and treatment is needed to treat this infection. We present a case of urinary tract infection during post partum period in a female who had recently delivered and was catheterized.Case report:-A 24 year old young female presented to the OPD with history of dysuria and fever . The fever was high grade and intermittent type. The female had delivered a male baby ten days earlier by cesarian section she had been catheterised for 10 days . General physical examination was normal except for elevated temperature . Heamogram revealed TLC of 12000 . Chest X ray was normal. Urine was sent for culture and sensitivity in our lab. The urine was inoculated on HiCrome agar using a calibrated loop. Inoculated plates were incubated at 35 degree C for 24 hours. Next day plates were examined for colony morphology.Gram smear showed short rod shaped cells ,0.5-0.8 µm. colonies were glossy, white 2-3mm. Providencia rettgeri Was isolated from urine and blood (figure 1).culture revealed that the isolate was resistant to ampicillin, ampicillin/sulbactam, cefazolin, gentamicin, and trimethoprim/ sulfamethoxazole. It was found to be susceptible to ceftriaxone, cefepime, ciprofloxacin, and piperacillin/tazobactam The patient was admitted put on iv ceftrioxone and had complete recovery.

Phenotypic and genomic characterization of pathogenic Providencia rettgeri from kuruma shrimp Marsupenaeus japonicus

“…Providencia rettgeri is a Gram‐negative and motile zoonotic pathogen in aquatic environments (Baldissera et al., 2019; Marull & Benedetti, 2009). It occasionally causes gastrointestinal illness, diarrhoea, xanthogranulomatous pyelonephritis, peritonitis, sepsis, and ventilator‐associated pneumonia in humans (Lee & Hong, 2011; Müller et al., 1986; Nazir et al., 2017; Patel et al., 2021; Sharma et al., 2017; T. K. M. Wang et al., 2014; Yoh et al., 2005). Providencia rettgeri can also be pathogenic to aquatic organisms, resulting in high mortality in the common silver carp Hypophthalmichthys molitrix , Nile tilapia Oreochromis niloticus , Chinese shrimp Fenneropenaeus chinensis , whiteleg shrimp Litopenaeus vannamei , rohu carp Labeo rohita , and turtle Trachemys scripta (Bejerano et al., 1979; Faisal et al., 1987; Gai et al., 2017; Ramesh & Souissi, 2018; Ye et al., 2020; Zhan et al., 1997).…”

Providencia Species – Involvement in Pathology and Multidrug Resistance in a Romanian County Hospital

“…The main Providencia species involved in human pathology are P. stuartii and P. rettgeri which can produce urinary tract infections, pneumonia, meningitis, wound infections, endocarditis, osteomyelitis, intraabdominal and bloodstream infections in hospitalized patients [1], [2], [9], [10], [11], [12].…”