Proton Therapy Expansion Under Current United States Reimbursement Models

Kerstiens, John; Johnstone, Peter A.S.

doi:10.1016/j.ijrobp.2014.02.014

Cited by 33 publications

(22 citation statements)

References 5 publications

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“…This is due primarily to the superior physical dose distribution over photons, which results in more precise dose delivery within the target and minimises dose to the normal structures in the vicinity of the tumour. An increasing number of centres worldwide are gradually acquiring proton therapy facilities [26], although the economic viability in some countries has been recently questioned [27] and additional 12 C ion therapy units would only add to the costs.…”

Section: Introductionmentioning

confidence: 99%

Could hyperthermia with proton therapy mimic carbon ion therapy? Exploring a thermo-radiobiological rationale

Datta

Puric

Schneider

et al. 2014

International Journal of Hyperthermia

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Hyperthermia has been conventionally used in conjunction with photon beam irradiation. With a gradual increase in particle therapy facilities worldwide, this paper explores the physical, thermal and radiobiological implications of using a combination of hyperthermia with proton beam therapy. Hyperthermia is known to exhibit radiobiological features similar to those of high linear energy transfer radiation. Protons have many of the physical dose distribution properties of (12)C ion therapy. Thus, the thermo-radiobiological advantages of hyperthermia coupled with the physical dose distribution advantages of proton beams could possibly mimic (12)C ion therapy.

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Section: Introductionmentioning

confidence: 99%

Could hyperthermia with proton therapy mimic carbon ion therapy? Exploring a thermo-radiobiological rationale

Datta

Puric

Schneider

et al. 2014

International Journal of Hyperthermia

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“…Historically, the high capital cost of proton facilities equipped with rotational gantries (exceeding US$160 million) 3 has limited the number of facilities in operation; however, that number is now increasing rapidly (see Table i). In the 10 years up to 2014, the number of facilities in the United States alone grew to thirteen from two 3 . Compact single-room cyclotron centres have drastically reduced the capital cost (estimated at less than US$50 million) and account for 10 of the 22 facilities under construction worldwide 2 .…”

Section: Introductionmentioning

confidence: 99%

Recommendations for the Referral of Patients for Proton-Beam Therapy, an Alberta Health Services Report: A Model for Canada?

et al. 2014

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able and willing to travel abroad to a proton facility. Commonly accepted indications for referral include chordoma and chondrosarcoma, intraocular melanoma, and solid tumours in children and adolescents who have the greatest risk for long-term sequelae. Current data do not provide sufficient evidence to recommend routine referral of patients with most head-and-neck, breast, lung, gastrointestinal tract, and pelvic cancers, including prostate cancer. It is recommended that all referrals be considered by a multidisciplinary team to select appropriate cases.

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“…The patient population trend presented in Figure 1 where only 3 major cohorts are shown reflects the referral pattern due to insurance coverage as shown in Figure 2. It clearly shows that the patient and site selection for proton beam in the USA may have a strong bias due to insurance coverage (23).…”

Section: Resultsmentioning

confidence: 99%

Proton Therapy Facility Planning From a Clinical and Operational Model

Das

Moskvin

Zhao

et al. 2014

Technol Cancer Res Treat

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This paper provides a model for planning a new proton therapy center based on clinical data, referral pattern, beam utilization and technical considerations. The patient-specific data for the depth of targets from skin in each beam angle were reviewed at our center providing megavoltage photon external beam and proton beam therapy respectively.Further, data on insurance providers, disease sites, treatment depths, snout size and the beam angle utilization from the patients treated at our proton facility were collected and analyzed for their utilization and their impact on the facility cost. The most common disease sites treated at our center are head and neck, brain, sarcoma and pediatric malignancies. From this analysis, it is shown that the tumor depth from skin surface has a bimodal distribution (peak at 12 and 26 cm) that has significant impact on the maximum

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Proton Therapy Expansion Under Current United States Reimbursement Models

Cited by 33 publications

References 5 publications

Could hyperthermia with proton therapy mimic carbon ion therapy? Exploring a thermo-radiobiological rationale

Could hyperthermia with proton therapy mimic carbon ion therapy? Exploring a thermo-radiobiological rationale

Recommendations for the Referral of Patients for Proton-Beam Therapy, an Alberta Health Services Report: A Model for Canada?

Proton Therapy Facility Planning From a Clinical and Operational Model

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