An all-optical approach to edge-enhanced proton radiography is realized by using a relativistic vortex laser irradiating on nanometer-thick foil. In the proof-of-principle experiments, the hollow proton beam was successfully produced by the transparent target normal electric field sheath in the break-out after-burner acceleration mechanism, using a superintense Laguerre–Gauss laser with the highest intensity of the laser exceeded 1020 W/cm2. An insect was imaged with the proton beam; the leg structures on the edge were clearly captured. By contrast, the dot proton source produced by a Gaussian laser was almost completely blocked by the insect's body, losing most edge information. Hollow-structured proton beams driven by vortex lasers conquer the dot imaging limit for high-energy proton beams, which may benefit imaging of capsule implosions in inertial confined fusion, instability research on expanding plasma, and precise positioning in medical therapy.