Prothrombin complex for massive obstetric haemorrhage

Glynn, Joanne; Plaat, F.

doi:10.1111/j.1365-2044.2007.04972.x

Cited by 9 publications

(2 citation statements)

References 5 publications

(7 reference statements)

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“…Prothrombin complex concentrates contain several important coagulation factors and it has been suggested that they could replace FFP. This has been shown mainly in case reports or series in which coagulation factor deficit was detected by using POC viscoelastic tests in trauma 47 or traditional hemostatic tests in obstetric patients 56 .…”

Section: Additional Strategiesmentioning

confidence: 99%

Management of postpartum haemorrhage

Bonnet

Benhamou

2016

F1000Res

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Postpartum Haemorrhage (PPH) is a major cause of maternal morbidity and mortality. Treatment of acquired coagulopathy observed in severe PPH is an important part of PPH management, but is mainly based on literature in trauma patients, and data thus should be interpreted with caution. This review describes recent advances in transfusion strategy and in the use of tranexamic acid and fibrinogen concentrates in women with PPH.

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Section: Additional Strategiesmentioning

confidence: 99%

Management of postpartum haemorrhage

Bonnet

Benhamou

2016

F1000Res

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“…There is one case report on the successful use of prothrombin complex concentrate (including coagulation factors II, VII, IX, and X) in the treatment of massive and intractable haemorrhage after a caesarean section 51 . Prothrombin complex concentrate is recommended for use in the treatment or prophylaxis of haemorrhage in patients with vitamin K deficiency, liver disease, or congenital deficiency of the relevant clotting factors.…”

Section: Coagulation Factor Concentratesmentioning

confidence: 99%

Management of post‐partum haemorrhage

Ahonen¹,

Stefanović²,

Lassila

2010

Acta Anaesthesiol Scand

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Management of post-partum haemorrhage (PPH) involves the treatment of uterine atony, evacuation of retained placenta or placental fragments, surgery due to uterine or birth canal trauma, balloon tamponade, effective volume replacement and transfusion therapy, and occasionally, selective arterial embolization. This article aims at introducing pregnancy- and haemorrhage-induced changes in coagulation and fibrinolysis and their relevant compensatory mechanisms, volume replacement therapy, optimal transfusion of blood products, and coagulation factor concentrates, and briefly cell salvage, management of uterine atony, surgical interventions, and selective arterial embolization. Special attention, respective management, and follow-up are required in women with bleeding disorders, such as von Willebrand disease, carriers of haemophilia A or B, and rare coagulation factor deficiencies. We also provide a proposal for practical instructions in the treatment of PPH.

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Pregnancy

Katz

2020

Trauma Induced Coagulopathy

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Prothrombin complex for massive obstetric haemorrhage

Cited by 9 publications

References 5 publications

Management of postpartum haemorrhage

Management of postpartum haemorrhage

Management of post‐partum haemorrhage

Pregnancy

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