Proteus syndrome: a case report and a case study review in China

Abstract

Proteus syndrome (PS) is a rare and sporadic disorder characterized by overgrowth of multiple tissues and a propensity to develop particular neoplasms. The clinical manifestations of PS include macrodactyly, vertebral abnormalities, asymmetric limb overgrowth and length discrepancy, hyperostosis, abnormal and asymmetric fat distribution, asymmetric muscle development, connective tissue nevi, and vascular malformations. We report a 16-year old female patient who manifested a number of these complications and review the Chinese literature about the diagnosis, natural history, and management of PS.

Xylazine Poisoning in Clinical and Forensic Practice: Analysis Method, Characteristics, Mechanism and Future Challenges

“…To identify the characteristics of xylazine poisoning cases in clinical and forensic practice, we searched "Xylazine poisoning" in PubMed and CNKI, excluded the cases without humans involved, and identified 20 papers which included more than 160 cases; the related information is summarized in Tables 2 and 3 [8,10,11,13,15,[28][29][30][34][35][36][37][38][39][40][41][42][43][44][45]. As shown in Table 2, most of the involved cases were accidental; however, homicide and suicide were also seen in the xylazine poisoning cases.…”

A case of Proteus syndrome with a large atrial septal defect

“…Most specifically associated tumours are monomorphic adenomas of the parotid glands and bilateral ovarian cystadenomas (2). Not only tumours but there are other complications; progressive skeletal deformities, invasive lipomas, deep vein thrombosis and pulmonary embolism (10).…”