Proteomics of left ventricular structure in the Multi‐Ethnic Study of Atherosclerosis
Tess E. Peterson,
Joao A.C. Lima,
Sanjiv J. Shah
et al.
Abstract:AimsProteomic profiling offers an expansive approach to biomarker discovery and mechanistic hypothesis generation for LV remodelling, a critical component of heart failure (HF). We sought to identify plasma proteins cross‐sectionally associated with left ventricular (LV) size and geometry in a diverse population‐based cohort without known cardiovascular disease (CVD).Methods and resultsAmong participants of the Multi‐Ethnic Study of Atherosclerosis (MESA), we quantified plasma abundances of 1305 proteins using… Show more
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