Proteomics, Human Environmental Exposure, and Cardiometabolic Risk
Andrew S. Perry,
Kai Zhang,
Venkatesh L. Murthy
et al.
Abstract:Rationale:
The biological mechanisms linking environmental exposures with cardiovascular disease (CVD) pathobiology are incompletely understood. We sought to identify circulating proteomic signatures of environmental exposures, and examine their associations with cardiometabolic and respiratory disease (CMD) in observational cohort studies.
Methods:
We tested the relations of >6500 circulating proteins with 29 environmental exposures across the built… Show more
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