Proteomics and Metabolic Characteristics of Boar Seminal Plasma Extracellular Vesicles Reveal Biomarker Candidates Related to Sperm Motility
Yu Zhang,
Ning Ding,
Jinkang Cao
et al.
Abstract:Although seminal plasma extracellular vesicles (SPEVs)
play important
roles in sperm function, little is known about their metabolite compositions
and roles in sperm motility. Here, we performed metabolomics and proteomics
analysis of boar SPEVs with high or low sperm motility to investigate
specific biomarkers affecting sperm motility. In total, 140 proteins
and 32 metabolites were obtained through differentially expressed
analysis and weighted gene coexpression network analysis (WGCNA).
Seven differentially … Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.