Proteomic profiling of gill GSTs in Mytilus galloprovincialis from the North of Portugal and Galicia evidences variations at protein isoform level with a possible relation with water quality

Azevedo, Catarina C.; Guzmán-Guillén, Remedios; Martins, José; Osório, Hugo; Vasconcelos, Vı́tor; Fonseca, Rute R. da; Campos, Alexandre

doi:10.1016/j.marenvres.2015.08.008

Cited by 22 publications

(9 citation statements)

References 57 publications

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“…We also detected high spatial variations in the proteome profiles among the four regions, thereby suggesting strong regulation of protein expression by the heterogeneous environmental conditions along the nationwide latitudinal gradient in Japan. These results support those obtained in studies using a terrestrial insect A. mellifera (Parker et al., ), marine mussel Mytilus galloprovincialis (Azevedo et al., ), and plant Kobresia pygmaea (Li et al., ), which found high proteome variations along geographically separated locations with large environmental variations. This may be a consequence of metabolic control (Tyson et al., ) and protein synthesis mechanisms (Mosier et al., ), which confer fitness benefits against local environmental pressures despite the specific requirements of organisms in terms of their physiology and feeding behavior, as well as diseases.…”

Section: Discussionsupporting

confidence: 89%

Differences in protein expression among five species of stream stonefly (Plecoptera) along a latitudinal gradient in Japan

Gamboa

Tsuchiya

Matsumoto

et al. 2017

Arch Insect Biochem Physiol

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Proteome variation among natural populations along an environmental gradient may provide insights into how the biological functions of species are related to their local adaptation. We investigated protein expression in five stream stonefly species from four geographic regions along a latitudinal gradient in Japan with varying climatic conditions. The extracted proteins were separated by two-dimensional gel electrophoresis and identified by matrix-assisted laser desorption/ionization of time-of-flight (MALDI TOF/TOF), yielding 446 proteins. Low interspecies variation in the proteome profiles was observed among five species within geographical regions, presumably due to the co-occurring species sharing the environments. However, large spatial variations in protein expression were found among four geographic regions, suggesting strong regulation of protein expression in heterogeneous environments, where the spatial variations were positively correlated with water temperature. We identified 21 unique proteins expressed specifically in a geographical region and six common proteins expressed throughout all regions. In warmer regions, metabolic proteins were upregulated, whereas proteins related to cold stress, the photoperiod, and mating were downregulated. Oxygen-related and energy-production proteins were upregulated in colder regions with higher altitudes. Thus, our proteomic approach is useful for identifying and understanding important biological functions related to local adaptations by populations of stoneflies.

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Section: Discussionsupporting

confidence: 89%

Differences in protein expression among five species of stream stonefly (Plecoptera) along a latitudinal gradient in Japan

Gamboa

Tsuchiya

Matsumoto

et al. 2017

Arch Insect Biochem Physiol

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“…GSTs are very important for xenobiotic detoxification at the molecular level. They are possibly part of the defense mechanisms of animals against adverse effects of environmental factors (43). The appearance of these GST-related DEGs in the comparisons of groups P vs. C and L vs. C in the F 1 offspring implies the memory of maternal stimuli from F 0 to F 1 animals.…”

Section: Discussionmentioning

confidence: 99%

Transgenerational transmission of maternal stimulatory experience in domesticated birds

Liu

et al. 2018

The FASEB Journal

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The environmental stimuli experienced by a female can influence phenotypes and gene expression in the subsequent generations. We used a specifically designed domesticated‐bird model to examine the transgenerational transmission of maternal stimulus exposure, a phenomenon that has been observed but has not been understood in noninbred animals. We subjected parental generation [filial (F)0] hens to viral‐ or bacterial‐like stimulation after artificial insemination. Subsequent filial generations F1 and F2 transmitted growth or fertility variations without further stimulation in contrast to the controls. The whole‐genome bisulfite sequence and next‐generation mRNA sequencing of peripheral blood lymphocytes (PBLs) from the F1 generation revealed DNA methylome and transcriptome differences in the F1 polyriboinosinic:polyribocytidylic [poly(I:C)] acid or LPS offspring, compared with the F1 controls. In the F1 offspring, DNA methylation changes induced by maternal immune stimulation may have contributed to transcriptional variation. Pathways analysis indicated that the metabolic processes of xenobiotics and drug metabolism pathways, as well as reproduction‐related pathways, were involved in the transgenerational transmission of maternal stimulatory experience. Furthermore, LPS‐induced transcriptional transmission may have contributed to subfertility, as indicated by the results of comparative analysis between the transcriptomes of spleen tissues across the F0 and F1 generations, as well as the correlative analysis between the transcriptome and reproductive phenotypes. Our findings provide a framework for determining the mechanisms by which maternal stimulatory factors can be inherited transgenerationally with respect to growth, fertility, DNA methylation, and transcriptional levels in outbred animals.—Liu, L., Yang, N., Xu, G., Liu, S., Wang, D., Song, J., Duan, Z., Yang, S., Yu, Y. Transgenerational transmission of maternal stimulatory experience in domesticated birds. FASEB J. 32, 7002–7017 (2018). htto://www.fasebj.org

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“…In such a context, either alone or combined, OMICs have been extensively used in a plethora of different subjects within life sciences. These include human health [ 29 ], animal sciences [ 30 ] and aquatic and environmental sciences [ 31 , 32 ]. Numerous reviews may be found in the subject and certain OMICs, namely proteomics, has been pointed out as being of particular relevance for animal, veterinary and aquatic science [ 33 , 34 , 35 ].…”

Section: Omics Overviewmentioning

confidence: 99%

OMICs Approaches in Diarrhetic Shellfish Toxins Research

Campos

Freitas

Almeida

et al. 2020

Toxins

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Diarrhetic shellfish toxins (DSTs) are among the most prevalent marine toxins in Europe’s and in other temperate coastal regions. These toxins are produced by several dinoflagellate species; however, the contamination of the marine trophic chain is often attributed to species of the genus Dinophysis. This group of toxins, constituted by okadaic acid (OA) and analogous molecules (dinophysistoxins, DTXs), are highly harmful to humans, causing severe poisoning symptoms caused by the ingestion of contaminated seafood. Knowledge on the mode of action and toxicology of OA and the chemical characterization and accumulation of DSTs in seafood species (bivalves, gastropods and crustaceans) has significantly contributed to understand the impacts of these toxins in humans. Considerable information is however missing, particularly at the molecular and metabolic levels involving toxin uptake, distribution, compartmentalization and biotransformation and the interaction of DSTs with aquatic organisms. Recent contributions to the knowledge of DSTs arise from transcriptomics and proteomics research. Indeed, OMICs constitute a research field dedicated to the systematic analysis on the organisms’ metabolisms. The methodologies used in OMICs are also highly effective to identify critical metabolic pathways affecting the physiology of the organisms. In this review, we analyze the main contributions provided so far by OMICs to DSTs research and discuss the prospects of OMICs with regard to the DSTs toxicology and the significance of these toxins to public health, food safety and aquaculture.

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Proteomic profiling of gill GSTs in Mytilus galloprovincialis from the North of Portugal and Galicia evidences variations at protein isoform level with a possible relation with water quality

Cited by 22 publications

References 57 publications

Differences in protein expression among five species of stream stonefly (Plecoptera) along a latitudinal gradient in Japan

Differences in protein expression among five species of stream stonefly (Plecoptera) along a latitudinal gradient in Japan

Transgenerational transmission of maternal stimulatory experience in domesticated birds

OMICs Approaches in Diarrhetic Shellfish Toxins Research

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