Proteomic Insights into Metastatic Breast Cancer Response to Brain Cell-Secreted Factors
Shreya Ahuja,
Iulia M. Lazar
Abstract:The most devastating feature of cancer cells is their ability to metastasize to distant sites in the body. HER2+ and triple negative breast cancers frequently metastasize to the brain and stay potentially dormant for years, clinging to the microvasculature, until favorable environmental conditions support their proliferation. The sheltered and delicate nature of the brain prevents, however, early disease detection, diagnosis, and effective delivery of therapeutic drugs. Moreover, the challenges associated with… Show more
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