“…However, the up-regulated proteins and mRNA activities often do not correspond to each other as a result of post-translational activities ( Pradet-Balade et al., 2001 ), which suggests that genome and transcriptome findings alone cannot be used to determine plant gene function and the regulatory mechanisms of plants under stress conditions. Meanwhile, other studies have shown that plant response to changing environmental conditions is directly linked with the upregulation of defense-related proteins ( Kerry et al., 2018 ; Liu L. et al., 2019 ; Sinha et al., 2021 ), which means that proteomics could provide mechanistic insights into the function of differently expressed proteins during cotton stress acclimation ( Chen et al., 2020 ) and developmental processes ( Zhu et al., 2018 ). The term “proteome” refers to the protein component of a given sample (organisms or plants), while “proteomics” refers to the quantification and identification of these proteins ( Wilkins et al., 1996 ).…”