“…Additionally, the identified proteins included 2 hypothetical conserved proteins and 3 proteins with unknown function (ribonucleoprotein p18, protein transport protein Sec13, and i/6 autoantigen-like protein). As expected, some of the proteins identified in the present work have been previously associated with humoral responses in VL and tegumentary leishmaniasis (TL) and are considered important candidate antigens for diagnosis, such as enolase [ 55 ], chaperonin HSP60 [ 56 ] and LACK [ 57 , 58 , 59 ]. Interestingly, enolase, LACK, cyclophilin, eukaryotic intiation factor 4a and chaperonin HSP60, have been identified in the secretome of different Leishmania parasites, further enhancing their use in diagnostic applications or as potential immunoprophylactic antigens [ 60 , 61 , 62 ].…”