Proteolytic activity in sea urchin gametes

Secretory functions of egg cortical granules in fertilization and development: A critical review

“…If correct, these findings suggest that a "cascade" reaction analogous to that responsible for blood coagulation may result in the sequential activation of several proteases during the cortical reaction at fertilization, as previously suggested [Lundblad, 1954;Runnstrom, 1966;Schuel et al, 19731. However, other investigators reported that S purpuratus eggs contained and secreted a single serine protease at fertilization [Fodor et al, 19751.…”

Developmental Physiology

“…protein and amino acid products which are utilized for synthesis of new sub stances. The very interesting studies of Hoberman et al (29) and Lundblad (30) constitute evidence in support of this view. Further studies of im portance on nucleic acid and protein synthesis in early sea urchin embryos have been reported by Abrams (31) and Gustafson & Hjelte (32).…”

On Some Properties of the Jelly Coat in Oocytes and Mature Eggs of Sea Urchins. A Study of Phase-Dependent Changes of Metaplasmic Layers in the Cell Surface

“…In fact, Lundblad (1950Lundblad ( , 1954 found that proteolytic enzymes may be present in the jelly substance and they may even be released to the medium. Lundblad (1950) first believed that the proteolytic enzymes were components of the jelly coat but later arrived at the conclusion that the proteolytic enzymes leak out from the surface of the unfertilized egg.…”

“…Lundblad (1950) first believed that the proteolytic enzymes were components of the jelly coat but later arrived at the conclusion that the proteolytic enzymes leak out from the surface of the unfertilized egg. The enzyme mainly involved is E 2, an enzyme with its pH optimum about neutral reaction.…”