“…The microorganims interact with the Plg-Plm system in different ways; by immobilizing Plg on their surfaces through Plg receptors (PlgR) an event that conducts to activation of Plg by host plasminogen activators (PAS) to generate enzymatically active Plm, or by expressing molecules that can activate Plg by themselves. PlgR have been detected in virus (Chaipan et al, 2009), fungus (Crowe et al, 2003), parasites (Avilán et al, 2011) and bacteria. Among bacteria are Borrelia burgdorferi (Fuchs et al, 1994), Escherichia coli (Kukkonen et al, 1998;Lähteenmäki et al, 1993;Parkkinen et al, 1991), Salmonella typhimurium (Korhonen et al, 1997;Kukkonen et al, 1998;Lähteenmäki et al, 1995), Neisseria meningitidis (Ullberg et al, 1992) and Haemophilus influenzae (Sjostrom et al, 1997) and group A, B and C of streptococci (Lähteenmäki et al, 2001b;Coleman & Benach, 1999).…”