Proteins and Protein Structure

Kurochkina, Natalya

doi:10.1007/978-981-13-6601-7_1

Cited by 2 publications

(3 citation statements)

References 187 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We examined interactions between pristine PhG NPs and several globular proteins, namely bovine serum albumin (BSA), lysozyme, and globulin (immunoglobulin), being motivated by the similarity in their shapes and dimensions but the difference in peptidic structures and isoelectric points (pI) (Table S1). At pH = 7.4, BSA (pI ∼ 4.7–4.9), lysozyme (pI ∼ 10.5–11.0), and globulin (pI ∼ 7.2) exhibit negative, positive, and neutral charges, respectively, which could provide insights into the nature of PhG NP–protein interactions that were studied using DLS and isothermal titration calorimetry (ITC), the gold standard for the quantitative analysis of intermolecular interactions …”

Section: Resultsmentioning

confidence: 99%

“…Although all selected proteins have chemical groups that can form hydrogen bonds with PhG NPs, the strength of such bonding for lysozyme and globulin in comparison with BSA was not sufficient to be measured. We attribute this effect to the difference in the composition and distributions of the peptidic building blocks and binding site architecture …”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Stimulus-Responsive Nanoconjugates Derived from Phytoglycogen Nanoparticles

Adibnia

Mitrache

et al. 2022

Biomacromolecules

View full text Add to dashboard Cite

Plant-derived phytoglycogen nanoparticles (PhG NPs) have the advantages of size uniformity, dispersibility in water, excellent lubrication properties, and lack of cytotoxicity; however, their chemical functionalization may lead to loss of NP structural integrity. Here, we report a straightforward approach to the generation of PhG NP conjugates with biologically active molecules. Hydrogen bonding of bovine serum albumin with electroneutral PhG NPs endows them with additional ligand binding affinity and enables the electrostatically governed attachment of methotrexate (MTX), a therapeutic agent commonly used in the treatment of cancer and arthritis diseases, to the protein-capped NPs. We showed stimuli-responsive release of MTX from the PhG-based nanoconjugates under physiological cues such as temperature and ionic strength. The results of this study stimulate future exploration of biomedical applications of nanoconjugates of PhG NPs.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Stimulus-Responsive Nanoconjugates Derived from Phytoglycogen Nanoparticles

Adibnia

Mitrache

et al. 2022

Biomacromolecules

View full text Add to dashboard Cite

show abstract

“…Enzymes are comprised of a globular protein component (biopolymer) and cofactors (Datta et al, 2013). They act as natural catalysts and increase the rate of biochemical reactions (Kurochkina, 2019). Enzymes can be intercellular or extracellular and have different protein structures ranging from secondary to quaternary.…”

Section: Enzymesmentioning

confidence: 99%

Novel Method of Essential oil Extraction from Spices

Meghwal

2023

JNFP

View full text Add to dashboard Cite

Essential oils have a wide range of industrial and pharmaceutical applications hence different novel technologies are recently being investigated to study the extraction of essential oils, enzyme assisted extraction is one of the recent green technology which is being studied extensively to see its effect on the yield of various components like essential oils and bioactive compounds. This review article summarises the spices in which enzyme-assisted extraction has been employed and its effect on the yield of the essential oil as well as the effect on the quality parameters of the oil, various studies, however, confirm that enzyme-assisted extraction increased the yield of the essential oil, which becomes a potential energy-efficient and cost-effective process and can be used at the industrial scale for a wide range of food, pharmaceutical applications.

show abstract

Proteins and Protein Structure

Cited by 2 publications

References 187 publications

Stimulus-Responsive Nanoconjugates Derived from Phytoglycogen Nanoparticles

Stimulus-Responsive Nanoconjugates Derived from Phytoglycogen Nanoparticles

Novel Method of Essential oil Extraction from Spices

Contact Info

Product

Resources

About