Proteínas de leptospiras reconhecidas durante a resposta imunológica humoral na leptospirose humana

Abstract

Nogueira, G. S. Leptospiral proteins recognized during the humoral immune response in human leptospirosis. [Dissertation]. São Paulo: Faculty of Medicine, University of São Paulo; 2023 Leptospirosis is a bacterial zoonosis caused by leptospires, with seasonal outbreaks, mainly in tropical and subtropical countries. It presents nonspecific symptoms, making clinical diagnosis difficult and, therefore, the laboratory diagnosis of leptospirosis is important for the confirmation of suspected cases and for the monitoring of the disease. Leptospires present a wide antigenic