Protein Phosphatase 4 Is Required for Centrobin Function in DNA Damage Repair
Zsuzsánna Réthi-Nagy,
Edit Ábrahám,
Rita Sinka
et al.
Abstract:Genome stability in human cells relies on the efficient repair of double-stranded DNA breaks, which is mainly achieved by homologous recombination (HR). Among the regulators of various cellular functions, Protein phosphatase 4 (PP4) plays a pivotal role in coordinating cellular response to DNA damage. Meanwhile, Centrobin (CNTRB), initially recognized for its association with centrosomal function and microtubule dynamics, has sparked interest due to its potential contribution to DNA repair processes. In this s… Show more
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