Protein Pattern and the Bacteriostatic Effect of the Exudate in Acute Otitis Media

Siirala, Urpo; Vuori, M.

doi:10.3109/00016485409128698

Cited by 25 publications

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“…The high bacterial recovery rate in the present study may represent a high rate of treatment failure of acute otitis media as observes in other study. 5 Correlating immunoglobulin levels and antibacterial enzyme (lysozyme) with the microbial isolation rate from effusions seemed to support the idea that the microbial organisms may have been involved in OME because the positive bacterial culture rate was inversely related to the levels of antimicrobial agents in the effusions; 6 therefore, their presence in the effusions cannot be discounted as mere contaminants. H. Influenzae was the most common pathogen recovered from effusions in this study, and this organisms is known to cause serous effusion in the middle ear, when infected.…”

Section: Resultsmentioning

confidence: 92%

Microorganisms in Chronic Otitis Media With Effusion

2003

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A total of 100 patient with otitis media effusion obtained from patients suffering fromchronic otitis media with effusions was examined for bacterial smear and culture. Inmucoid effusion 82% showed positive bacterial smear, only 35% yielded positivebacterial culture. Bacterial cultures rate was higher in serous (50%) effusion. Theisolation of common pathogens accounted for the remaining 42%. The high incidenceof microorganisms in the middle ear effusions in the present study indicates bacterialcontribution in many cases of otitis media effusion. Concerning the sterile nature ofthe middle ear fluid some investigators suggested that the effusions are transudatesand are created by a negative pressure in the tympanum due to a malfunctioningEustachian tube.2It was suggested that failure to isolate organisms may be partly dueto the antimicrobial characteristics of effusions. The purpose of this study is to showpossible role of bacteria in Middle Ear Effusions.Key Words: Otitis Media, Effusion, Microorganisms.

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