Protein-Losing Enteropathy in Crohn's Disease: Two Unusual Cases

Abstract

Protein-losing enteropathy (PLE) occurs when protein losses throughout the gastrointestinal (GI) tract exceed the liver’s ability to produce new protein. This is a rare presentation of Crohn's disease and few reported cases of PLE related to Crohn’s exist in the literature. We describe two patients who presented with symptoms of PLE. After extensive diagnostic workup both were diagnosed with Crohn’s disease and managed with prednisone.