Protein insertion into the inner membrane of mitochondria: routes and mechanisms
Büsra Kizmaz,
Annika Nutz,
Annika Egeler
et al.
Abstract:The inner membrane of mitochondria contains hundreds of different integral membrane proteins. These proteins transport molecules into and out of the matrix, they carry out multifold catalytic reactions and they promote the biogenesis or degradation of mitochondrial constituents. Most inner membrane proteins are encoded by nuclear genes and synthesized in the cytosol from where they are imported into mitochondria by translocases in the outer and inner membrane. Three different import routes direct proteins into… Show more
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