Protein hydrolysates obtained from Azufrado (sulphur yellow) beans (Phaseolus vulgaris): Nutritional, ACE-inhibitory and antioxidative characterization

Solid State Bioconversion for Producing Common Bean (<i>Phaseolus</i> <i>vulgaris</i> L.) Functional Flour with High Antioxidant Activity and Antihypertensive Potential

“…The Figure 1 shows the non-linear fit plots of unproccesed and bioproccesed common beans hydrolysates ACE-I evaluations; it can be observed that hydrolysates from BCBF shows the nonlinear fit plots of unproccesed and bioproccesed common beans hydrolysates ACE-I evaluations; it can be observed that hydrolysates from BCBF showed the highest ACE inhibitory activity percentage (93%). Some researchers [11,13,50] have reported that common bean seeds are a valuable source of ACE inhibitors (ACE increases blood pressure by converting the inactive decapeptide angiotensin I to the potent vasoconstrictor angiotensin II and inactivating the vasodilator bradykinin [35]). Therefore, inhibition of ACE reduces the activity of angiotensin II but increases bradykinin levels, and thus can result in a lowering of blood pressure.…”

Solid State Bioconversion for Producing Functional Flours from Whole Quality Protein Maize and Common Beans with Enhanced Nutritional Value, Antioxidant and Antihypertensive Potential

“…Valdez-Ortiz et al [8] reported that common bean seeds are a valuable source of ACE inhibitors. Therefore, inhibition of ACE reduces the activity of Angiotensin II but increases Bradykinin levels, and thus can result in a lowering of blood pressure.…”

“…Therefore, inhibition of ACE reduces the activity of Angiotensin II but increases Bradykinin levels, and thus can result in a lowering of blood pressure. It has been reported that many natural ACE inhibitors isolated from the hydrolysis of various grains proteins such as amaranth [34] common beans [8] or during gastrointestinal digestion or food processing [35] can be used as pharmaceuticals and physiological functional food supplements for hypertension therapy. The results obtained in this work are encouraging, because IC 50 values were in agreement or lower than those reported for pancreatic hydrolysates from common beans (60-319 µg / mL) [8] and pepsin-pancreatin hydrolysates from lima bean (250-692 µg/mL) [36].…”

“…Common beans are rich in antioxidants which, among other components, provides flavonoids and phenolic acids ( Figure 2) [7]; likewise, this legume is a source for producing bioactive peptides (Table 2) obtained by enzymatic hydrolysis which confer antioxidant activity, antimutagenic effects [6] and an antihypertensive potential by inhibiting angiotensin converting enzyme [8,9]. In order to obtain maximum health benefits of whole grains, such as maize and beans, it is desirable to prepare mixtures from them; the additive and synergistic effects of biologically active components present in each whole grain may be responsible for the health benefits as the reduced risk of chronic diseases.…”

Antioxidant Properties of Protein Hydrolysates (Avena L.) From Grains of Cultivated and Wild Oat Species

“…Alkalaza okazała się również skutecznym enzymem w procesie uwalniania bioaktywnych peptydów m.in. z białek: serwatki (54,2 % aktywności przeciwrodnikowej, przy stężeniu próbki 0,10 mg/ml), amarantusa (50 % inhibicji ABTS +· przy stężeniu próbki 1,44 mg/ml), jak i fasoli (73,4 -99,9 % przy stężeniu próbki -0,25 mg/ml) [8,19,26].…”