Protein feature engineering framework for AMPylation site prediction
Hardik Prabhu,
Hrushikesh Bhosale,
Aamod Sane
et al.
Abstract:AMPylation is a biologically significant yet understudied post-translational modification where an adenosine monophosphate (AMP) group is added to Tyrosine and Threonine residues primarily. While recent work has illuminated the prevalence and functional impacts of AMPylation, experimental identification of AMPylation sites remains challenging. Computational prediction techniques provide a faster alternative approach. The predictive performance of machine learning models is highly dependent on the features used… Show more
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