Protein Electrophoresis in Saliva Study

Lamy, Elsa; Costa, Ana Rodrigues; Antunes, Célia M.; Vitorino, Rui; Amado, Francisco

doi:10.5772/48586

Cited by 5 publications

(9 citation statements)

References 108 publications

(125 reference statements)

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“…Macrophages are important cells of the immune system that function by attaching to foreign material and sending out signals that activate immune responses, which can lead to inflammation and rejection of an implant. For dental implants in particular, osteogenesis can be affected by the saliva in the mouth, which contains over 2000 proteins that may be entrapped during implantation into bone [12]. There are also 600 species of bacteria in the human oral microbiome [13] and the response of bacteria to a dental implant is an important consideration.…”

Section: On Osteogenesismentioning

confidence: 99%

Understanding the biological responses of nanostructured metals and surfaces

Lowe

Reiss

2014

IOP Conf. Ser.: Mater. Sci. Eng.

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Section: On Osteogenesismentioning

confidence: 99%

Understanding the biological responses of nanostructured metals and surfaces

Lowe

Reiss

2014

IOP Conf. Ser.: Mater. Sci. Eng.

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“…A number of proteomics researches contributed to the clarification and knowledge of the salivary proteome, and more than 2000 proteins and peptides have been found in WS and individual salivary glands [ 15 ]. Saliva is a mucoserous exocrine fluid produced by three major salivary glands (parotid, submandibular (SM), and sublingual (SL)) and other minor glands located under the oral mucosa [ 16 ].…”

Section: Whole Salivamentioning

confidence: 99%

Salivary Biomarkers in Systemic Sclerosis Disease

Zian

Bakkach

Barakat

et al. 2018

BioMed Research International

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Scleroderma or systemic sclerosis (SSc) is frequently detected at an advanced stage due to diagnosis difficulties. Salivary biomarkers, if existing, could be used for predictive diagnosis of this disease. Human saliva contains a large number of proteins that can be used for diagnosis and are of great potential in clinical research. The use of proteomic analysis to characterize whole saliva (WS) in SSc has gained an increasing attention in the last years and the identification of salivary proteins specific for SSc could lead to early diagnosis or new therapeutic targets. This review will present an overview about the use of WS in SSc studies. The proteomic technologies currently used for global identification of salivary proteins in SSc, as well as the advantages and limitations for the use of WS as a diagnostic tool, will be presented.

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“…Concerning stimulated saliva, it is frequently obtained after parafilm mastication, or after sour taste stimulation [62]. Advantages and disadvantages of each approach have been mentioned previously [63]. Another issue to be considered is the origin of collected secretions, i.e., whether it is glandular or whole saliva, since considerable differences exist in composition.…”

Section: Methodological Issues Related To the Use Of Electrophoresis mentioning

confidence: 99%