Protein Disulfide Isomerases

Schwaller, Melissa; Gilbert, Hiram F.

doi:10.1038/npg.els.0003021

Encyclopedia of Life Sciences 2001

DOI: 10.1038/npg.els.0003021

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Protein Disulfide Isomerases

Melissa Schwaller¹,

Hiram F. Gilbert²

Abstract: Protein disulfide isomerase is a multifunctional protein that facilitates the formation of disulfide crosslinks between cysteine residues during the early stages of protein folding and secretion. It is a member of a large family of oxidoreductases that catalyse exchange reactions between thiols and disulfides.

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Protein Disulfide Isomerases

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