Protein-deficient diets I. Activity of selected enzymes of protein and carbohydrate metabolism

Nikonorow, M; Urbanek-Karłowska, B; Karlowski, K.

doi:10.1016/0300-483x(73)90033-4

Cited by 6 publications

(4 citation statements)

References 15 publications

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“…Many indicators would argue that pharmacokinetics, and, therefore, drug action, can change with age 12 . Protein deprivation can produce hypoalbuminemia and changes in heart weight, 13–15 which can lead to altered distribution of drugs. Altered drug metabolism may occur when there is increased mixed‐function oxidase activity in response to increased dietary polyunsaturated or essential fatty acid intake, 16–20 and different forms of cytochrome P‐450 are affected differently by dietary carbohydrate manipulation.…”

Section: Pharmacokinetics and The Elderlymentioning

confidence: 99%

The Elderly, Undernutrition, and Pharmacokinetics

Lamy

1983

J American Geriatrics Society

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Section: Pharmacokinetics and The Elderlymentioning

confidence: 99%

The Elderly, Undernutrition, and Pharmacokinetics

Lamy

1983

J American Geriatrics Society

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“…Животные контрольной группы с момента звукового воздействия до конца опытов (40-е сут) получали cбалансированную или богатую белками пищу по рецепту, предложенному в работе [11] (табл. 1).…”

Section: материалы и методыunclassified

Ultrastructural Characteristics of Axodendritic and Axosomatic Synapses in the Orbitofrontal Cortex of White Laboratory Rats Associated with Low-Protein Food after Acute Sound Exposure

Sultanly

2022

BIOMEDICINE

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This paper investigates the state of axodendritic (ADS) and axosomatic (ASS) synapses in orbitofrontal cortex (OFC) layers I-IV of adult white laboratory rats associated with balanced and low-protein food after acute sound exposure. Experiments were performed on 64 white non-linear sexually mature laboratory male rats weighing 180–230 g (eight intact, 56 experimental). After a continuous call with an intensity of 120 db for 120 seconds, 56 rats were divided into two groups: those receiving balanced (control – 28) and low-protein food (basic – 28). Each of these two groups was divided into two subgroups: stress-resistant (12 animals in each) and stress-unstable animals (16 animals in each). Water intake was unlimited. The animals were removed from the experiment on the 10th, 20th, 30th, and 40th day after sound exposure. Along with histological and immunohistochemical analysis, the samples of OFC layers I–IV were studied by transmission electron microscopy. Electron microscopic changes in the structure of ADS and ASS were found in all OFC layers. Violations of the fine structure of both the presynaptic and postsynaptic poles were noted. The maximum severity of ultrastructural changes was observed in the ADS of the surface (I, molecular), outer granular (II), pyramidal (III), and inner granular (IV) OFC layers. ASS disorganization was noted mainly in contacts, the postsynaptic pole of which was formed by the bodies of small pyramidal neurons of layer III, as well as pyramidal and stellate neurons of layer IV of the OFC. During all periods of observation, violations of fine organization were most pronounced in stress-unstable animals of the main experimental group, especially on the 10th and 20th day after exposure. Acute sound exposure initiates disturbances in the fine organization of axodendritic and axosomatic synapses in OFC layers I–IV of white laboratory rats. Focal destruction of a part of the noted synapses in rats with a low-protein diet after acute auditory stress is irreversible.

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“…Материалы и методы: Эксперименты проводились на 120 белых лабораторных крысах в возрасте 3 и 12 месяцев. Животным в течении одного месяца давали пищу по следующему рецепту: крахмал -65,0 гр; подсолнечное масло -5,0 гр; целлюлоза -5,0 гр; витаминная смесь -1,0 гр; солевая смесь -0,4 гр (Nikinorov M., Urbanek-Karlowska B., Karlowska K., 1973). В качестве условных рефлексов применяли методы условной реакции активного избегания (УРАИ) и условной реакции пассивного избегания (УРПИ).…”

Section: лейла сулеймановаunclassified

Working Conditions and Health of Seafarers

Hasanova¹,

Hajizada²

2020

Proceedi̇ngs of the First International Scientific Practical Online Conference Human Genetics and Genetic Diseases: Problems A

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Panel 1. Development of genetic diagnostic methods, their use in clinical and scientific research. 10.30-10.45 Rauf Baylarov. AMU. Associate Professor. Heterogeneity of polymorphisms in the nephrin gene (NPHS1) and podocin (NPHS2) in Azerbaijani children with chronic glomerulonephritis. 10.45-11.05 Afig Bardali. Ege University. Doctor Professor. Recent approaches in genetic diagnosis and their application in modern diagnoses. 11.05-11.20 Orkhan İsayev. Azerbaijan Medical University. Associate Professor. Cancer stem cells. 11.20-11.35 Davit Tophuria. Tbilisi State Medical University. Associate Professor. Liver Toxic Damage in occupational exposure to solvents. 11.35-11.45 Coffee Break 11.45-12.00 Madina Azova. Peoples' Friendship University of Russia. Professor. Association of DNA methyltransferase gene polymorphism with early pregnancy loss. 12.00-12.15 Lyazzat Syrlybayeva. West Kazakhstan Marat Ospanov Medical University. PhD in Medicine. Preliminary results of the use of tandem mass spectrometry for hereditary metabolic diseases in the western region of Kazakhstan. 12.15-12.30 Afshin Zardoshtian, Amirreza Rabiee. Medical students. Multidisciplinary Science High School. Tbilisi State Medical University. Georgia

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Protein-deficient diets I. Activity of selected enzymes of protein and carbohydrate metabolism

Cited by 6 publications

References 15 publications

The Elderly, Undernutrition, and Pharmacokinetics

The Elderly, Undernutrition, and Pharmacokinetics

Ultrastructural Characteristics of Axodendritic and Axosomatic Synapses in the Orbitofrontal Cortex of White Laboratory Rats Associated with Low-Protein Food after Acute Sound Exposure

Working Conditions and Health of Seafarers

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