Protein-bound iodine in premature infants.

Chadd, M. A.; Davies, Dean F.; Gray, O.P.

doi:10.1136/adc.43.228.217

Cited by 6 publications

(5 citation statements)

References 7 publications

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“…Those full-term infants raised near or at thermoneutral temperatures had serum PBI concentrations which were only slightly elevated by adult standards. C iia d d et al [5] studied a population with distribution of body weight which was similar to ours; they found systematically elevated PBI levels (by adult standards). Their patients, however, were exposed to ambient temperatures consider ably below the thermoneutral zone [4].…”

Section: Discussionmentioning

confidence: 87%

“…[4][5][6][7][8][9][10][11][12] was assessed by comparing the measurements in matched pairs. At the end of 24 h under trial conditions, the standard infant had a higher V 0 2 than his warm match in 15 out of 18 pairs (S>W8/9; SS)W7/9).…”

Section: Resultsmentioning

confidence: 99%

“…When the entire series of 12 sets of infants is considered, the median intra-pair difference in rates of weight gain is about 19%. Since measurements of V 0 2were made in only 9 sets of infants [4][5][6][7][8][9][10][11][12], we will consider the relationships of resting metabolic rate to weight gain only in these infants. The median intra-pair difference in weight gain between W and S infants in these sets is about 2 g/kg/day or 13% (using the median daily weight gain of the warm infants as a reference point).…”

Section: Discussionmentioning

confidence: 99%

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Relationship of Thermal Environment and Caloric Intake to Growth and Resting Metabolism in the Late Neonatal Period

Glass

Silverman

Sinclair³

1969

Neonatology

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Section: Discussionmentioning

confidence: 87%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Relationship of Thermal Environment and Caloric Intake to Growth and Resting Metabolism in the Late Neonatal Period

Glass

Silverman

Sinclair³

1969

Neonatology

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“…plasma) (Perry, Hodgman, and Starr, 1965;Rose, Russell, and Starr, 1963). Both full-term (Danowski et al, 1950) and premature infants (Chadd, Davies, and Gray, 1968) showed a rise of the PBI values, above the upper limit of adult euthyroid normal, 8 ,ug./100 ml., during the first week of life. Values of [10][11][12][13][14] Htg./100 ml.…”

Section: Resultsmentioning

confidence: 99%

“…Values of [10][11][12][13][14] Htg./100 ml. were frequently obtained between 48 hours and 8 days of life by Chadd et al (1968) in premature infants. These values gradually fell over the next 2-3 months.…”

Section: Resultsmentioning

confidence: 99%

Thyroid Function Tests in the Newborn

Chadd¹,

Gray²,

Davies³

1970

Archives of Disease in Childhood

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. (1970). Archives of Disease in Childhood, 45, 374. Thyroid function tests in the newborn. The 131I triiodothyronine (T3) resin uptake test reflects thyroid function more closely than other acceptable tests currently available.The T3 uptake and protein-bound iodine (PBI) level were estimated in 20 premature and 20 full-term infants at birth and at the end of 1 week.The full-term infant has normal adult values, whereas the premature baby has results extending into the hyperthyroid range at birth, but these fall to within normal limits at 1 week.There are few studies of thyroid function in the newborn and neonatal period of infants bom earlier than the 37th week of gestation. Proteinbound iodine (PBI) levels are similar to those obtained for full-term infants (Danowski et al., 1950). The radioactive iodine (1311) uptake test has limited value because of the risk from irradiation.The in vitro test of radioactive 131I-labelled triiodothyronine uptake using red blood cells was introduced by Hamolsky, Stein, and Freedberg (1957). A similar test was used by later workers using a resin substituted for red blood cells (Nava and De Groot, 1962;Godden and Garnett, 1964 The tests were repeated on the 8th day of life. Plasma-bound iodine was estimated by Auto-analyser The 131I tri-iodothyronine (T,) resin uptake test was estimated after the method of Gimlette (1967). The T, adult euthyroid range is for this laboratory 70-140%.The T3 test can now be performed on as little as 0 1 ml. plasma. ResultsThe PBI levels in both the full-term and premature infants confirm the known high mean and wide ranges of cord blood, with even higher levels at the end of the first week (Table). However, T3 resin uptake is normal for the full-term infants both at birth and at the end of the first week. The premature infants' cord results show a high mean with a very wide range at birth, but by the end of the first week these results also show a normal mean and range.The mean cord blood PBI in both term and premature infants is at the upper limit of adult normal euthyroid values (3*5 fig.-8 0 tzg./100 ml.

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Rehabilitation After Myocardial Infarction

Gancz¹

1972

The Lancet

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Protein-bound iodine in premature infants.

Cited by 6 publications

References 7 publications

Relationship of Thermal Environment and Caloric Intake to Growth and Resting Metabolism in the Late Neonatal Period

Relationship of Thermal Environment and Caloric Intake to Growth and Resting Metabolism in the Late Neonatal Period

Thyroid Function Tests in the Newborn

Rehabilitation After Myocardial Infarction

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