Protein binding on acutely toxic and non-toxic polystyrene nanoparticles during filtration by Daphnia magna

Abstract

Toxic and non-toxic polystyrene particles bind different proteins during filtration by zooplankton.

Daphnia as a model organism to probe biological responses to nanomaterials—from individual to population effects via adverse outcome pathways

“…The biodegradation of organic surface coatings is relevant to all types of manufactured NMs and to MPs, and the gut microbiota of aquatic organisms are likely to play a key role (Nasser et al, 2020). Biomodification is an additional process that can affect the fate and toxicity of NMs, which includes processes that are indirectly mediated by organisms after NMs are taken up by the organisms (Kelpsiene et al, 2022).…”

“…These secreted biomolecules can form coronas on NMs and MPs as the biomolecules adsorb onto the surface of the particles. These coronas are dynamic in nature, and result from the adsorption of different types of available proteins, metabolites and polysaccharides, which also exchange between bound and free forms (Westmeier et al, 2016;Grintzalis et al, 2019;Kelpsiene et al, 2022). Environmental and biological constitutes that have a molecular weights spanning from 10 to 2,000,000 Da adsorb onto NMs surfaces forming the eco-corona, and affecting the stability, identity, uptake and toxicity of NMs towards Daphnia (Nasser et al, 2020).…”

“…In theory, the considerations applied to NMs for ecotoxicity testing can also be applied to MPs, as the physical interactions and surface conditioning of MPs will also occur in their local environments. Although a relatively emerging field, Daphnia have already been used for a range of MP toxicity studies to date, to elucidate the potential impacts that MPs induce in freshwater environments (Nasser and Lynch, 2016;Schür et al, 2020;Zimmermann et al, 2020;Kelpsiene et al, 2022).…”

Commercial photocatalyst changes the behavior of Formica pratensis and Formica polyctena

“…However, the general point of view is that the term of safety focuses more on humans. Moreover, nanomaterials safety is evaluated by using animal-based experiments 1,2 including other model organisms [3][4][5] . Nevertheless, a clear effect of nanomaterials on the environment is crucial.…”

“…Safety concerns are focused mainly on humans. However, nanomaterial safety is evaluated by using animal-based experiments 1,2 including other model organisms. [3][4][5] It is crucial to understand the effect of nanomaterials on the environment.…”