Protein adsorption kinetics in different surface potentials

Quinn, Anthony S.; Mantz, Hubert; Jacobs, Karin; Bellion, M.; Santen, Ludger

doi:10.1209/0295-5075/81/56003

Cited by 40 publications

(54 citation statements)

References 34 publications

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“…Recently, a similar influence was detected on the adsorption kinetics of proteins [11][12][13] and the adhesion of bacteria [14]. These experiments used materials whose contribution to the potential had been tuned by means of surface stratification.…”

Section: Introductionmentioning

confidence: 67%

Macroscale adhesion of gecko setae reflects nanoscale differences in subsurface composition

Loskill

Puthoff

Wilkinson

et al. 2013

J. R. Soc. Interface.

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Surface energies are commonly used to determine the adhesion forces between materials. However, the component of surface energy derived from long-range forces, such as van der Waals forces, depends on the material's structure below the outermost atomic layers. Previous theoretical results and indirect experimental evidence suggest that the van der Waals energies of subsurface layers will influence interfacial adhesion forces. We discovered that nanometre-scale differences in the oxide layer thickness of silicon wafers result in significant macroscale differences in the adhesion of isolated gecko setal arrays. Si/SiO 2 bilayer materials exhibited stronger adhesion when the SiO 2 layer is thin (approx. 2 nm). To further explore how layered materials influence adhesion, we functionalized similar substrates with an octadecyltrichlorosilane monolayer and again identified a significant influence of the SiO 2 layer thickness on adhesion. Our theoretical calculations describe how variation in the SiO 2 layer thickness produces differences in the van der Waals interaction potential, and these differences are reflected in the adhesion mechanics. Setal arrays used as tribological probes provide the first empirical evidence that the 'subsurface energy' of inhomogeneous materials influences the macroscopic surface forces.

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Section: Introductionmentioning

confidence: 67%

Macroscale adhesion of gecko setae reflects nanoscale differences in subsurface composition

Loskill

Puthoff

Wilkinson

et al. 2013

J. R. Soc. Interface.

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“…This is done by defining proteins as single particles that may be spherical, disk shaped, hexagonal, or rectangular, with a specific charge or binding site located somewhere within or at the edge of the particle [138,[295][296][297][298][299][300]. The adsorption process is then simulated with a Metropolis Monte-Carlo simulation according to appropriate algorithms.…”

Section: Computational Approachesmentioning

confidence: 99%

Understanding protein adsorption phenomena at solid surfaces

Rabe

Verdes

Seeger

2011

Advances in Colloid and Interface Science

1,345

1,239

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Protein adsorption at solid surfaces plays a key role in many natural processes and has therefore promoted a widespread interest in many research areas. Despite considerable progress in this field there are still widely differing and even contradictive opinions on how to explain the frequently observed phenomena such as structural rearrangements, cooperative adsorption, overshooting adsorption kinetics, or protein aggregation. In this review recent achievements and new perspectives on protein adsorption processes are comprehensively discussed. The main focus is put on commonly postulated mechanistic aspects and their translation into mathematical concepts and model descriptions. Relevant experimental and computational strategies to practically approach the field of protein adsorption mechanisms and their impact on current successes are outlined.

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“…It could be shown that, when interacting with a coated substrate, proteins indeed sense both, the surface layer and the underlying material: Adsorption experiments on tailored silicon wafers with differences in the thickness of the oxide layer on top of the wafers revealed qualitatively different adsorption kinetics of multiple types of proteins. 41,42 Based on Monte-Carlo simulations featuring surface processes such as surface mobility and conformational changes, the distinctions were invoked by the influence of the vdW-interactions on the time scale of these processes. 43 X-ray reflectivity experiments corroborated these findings.…”

Section: Interactions In Biological Systemsmentioning

confidence: 99%

Is adhesion superficial? Silicon wafers as a model system to study van der Waals interactions

Loskill¹,

Hähl²,

Faidt³

et al. 2012

Advances in Colloid and Interface Science

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Adhesion is a key issue for researchers of various fields, it is therefore of uppermost importance to understand the parameters that are involved. Commonly, only surface parameters are employed to determine the adhesive forces between materials. Yet, van der Waals forces act not only between atoms in the vicinity of the surface, but also between atoms in the bulk material. In this review, we describe the principles of van der Waals interactions and outline experimental and theoretical studies investigating the influence of the subsurface material on adhesion. In addition, we present a collection of data indicating that silicon wafers with native oxide layers are a good model substrate to study van der Waals interactions with coated materials.

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Protein adsorption kinetics in different surface potentials

Cited by 40 publications

References 34 publications

Macroscale adhesion of gecko setae reflects nanoscale differences in subsurface composition

Macroscale adhesion of gecko setae reflects nanoscale differences in subsurface composition

Understanding protein adsorption phenomena at solid surfaces

Is adhesion superficial? Silicon wafers as a model system to study van der Waals interactions

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