Protective Role of Medicinal Herb Anethum Graveolens (Dill) Against Various Human Diseases and Metabolic Disorders

Mohammed, Furkhan Ahmed; Razvi, Syed Shoeb; Abdul, Waseem Mohammed; Mohammed, Kaleemuddin; Hakeem, Khalid Rehman; Banaganapalli, Babajan; Shaik, Noor Ahmad; Elkady, Ayman I.

doi:10.1007/978-3-030-04408-4_8

Cited by 6 publications

(6 citation statements)

References 49 publications

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“…In this way, many studies have indicated that the presence of antioxidants in the diet can increase the growth of fish (NRC 2011). Third, the presence of fiber and vitamins A, C, B 1, and B 2 in dill (Mohammed et al 2019) could have contributed to the increase in growth that we achieved in our study, based on the effects of vitamins on fish growth that are broadly described (NRC 2011). Finally, we can propose that the stimulation of secretion of digestive enzymes, improvement of digestibility, and absorption of nutrients that is facilitated by dill can be a reason for the increasing growth performance, as has been reported in studies that used garlic (Esmaeili et al 2017a).…”

Section: Controlmentioning

confidence: 90%

The Effect of Extract from Dill Anethum Graveolens on the Growth Performance, Body Composition, Immune System, and Antioxidant System of Rainbow Trout

et al. 2020

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In recent years, supplementing herbal medicines to fish diets in the aquaculture industry as a growth stimulant and immunostimulant is a common practice. In the present study, we investigated the effect of hydroalcoholic extract of dill on the growth performance and body composition of Rainbow Trout Oncorhynchus mykiss and its inhibitory effect against Aeromonas hydrophila in vitro. We also evaluated the immune responses and antioxidant system in fish that were fed dill diets over a period of 56 d. For this purpose, 180 Rainbow Trout fingerlings (initial weight 13.30 ± 0.22 g; mean ± SD) were purchased and they were fed four experimental treatments, which included a control diet and diets that were supplemented with 1Dill (1 g/kg dill extract), 1.5Dill (1.5 g/kg dill extract), or 3Dill (3 g/kg dill extract). According to the results, the fish that were fed 1Dill (54.70 g) and 1.5Dill (53.19 g) diets had significantly higher weight gain, although the feed conversion ratio was not significantly different among groups. However, the fish that were fed the 1.5Dill (62.55%) diet had significantly higher protein contents in the body than those that were fed the 3Dill (60.09%) treatment; the fish that were fed the 3Dill (29.00%) diet had higher lipid content than those that were fed the other diets. Regarding immune and antioxidant systems, the Rainbow Trout that were fed the 1.5Dill diet had significantly higher values of lysozyme in their serum (53.33 U/mL), alternative complement pathway hemolytic activity (146.33 U/mL), superoxide dismutase (52.33 U/mg protein), and catalase activity (164.66 U/mg protein) than the others did. Dill extracts in different dosages had no inhibitory effect against A. hydrophila in vitro. In summary, it can be concluded that the 1.5Dill diet can be used as a natural stimulant of growth, immunity, and the antioxidant system in the aquaculture industry.

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Section: Controlmentioning

confidence: 90%

The Effect of Extract from Dill Anethum Graveolens on the Growth Performance, Body Composition, Immune System, and Antioxidant System of Rainbow Trout

et al. 2020

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“…In recent years, the use of herbal products/medicinal herbs containing bioactive compounds has been the subject of discussion in many studies. 1 The bioactive properties of plants as phytomedicines or supplements have shown effective results in nutritional therapy for the treatment of various diseases, 2 boosting immunity, minimizing the risk of chronic diseases, and boosting the maintenance of health. 3 A high percentage of new drugs are based on active molecules or/ and their derivatives from plants for the preparation of immunosuppressants, anticancer drugs, 4 and their antioxidant phytochemicals neutralize free radicals and help treat chronic diseases.…”

Section: Introductionmentioning

confidence: 99%

Impact of dietary supplementation with chokeberry (Aronia melanocarpa, Michx.) on tetrachloride‐induced liver injury in Wistar rats: Hematological and biochemical implication

Suljević

Mitrašinović-Brulić

Klepo

et al. 2023

Cell Biochemistry & Function

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In the current study, we assessed the hematological/biochemical alterations, histopathological changes in the liver, and blood cell disorders in Wistar rats exposed to a toxic concentration of carbon tetrachloride (CCl4) and the potential protective effect of a 30‐day oral extract of chokeberry (Aronia melanocarpa, AM). The concentration of AM (3.38 mg/kg) obtained by quantitative purification from AM fruit showed the highest antioxidant activity (AOA) in vitro and was used for oral ingestion. In addition to high AOA, high values of total phenols (85.334 mg/g), total phenolic acid (606.95 mg/g), total flavonids (22.10 mg/g), and total anthocyanins (11.01 mg/g) were recorded in chokeberry extract. CCl4 treatment caused serious liver injury, hepatocyte and blood cell impairment. AM extract given to rats before CCl4 application had a moderate hepatoprotective effect in comparison to after CCl4 application. White blood count and leukocytes were significantly altered by CCl4, however, the protective role of AM in leukocyte disorders was not established. A high number of microcytes, stomatocytes, anisocytes, and hemolyzed erythrocytes during CCl4 exposure was reduced by AM extract. Flower erythrocytes in the AM + CCl4 group were recorded. Supplementation with chokeberry extract without CCl4 caused hyperproteinemia and hyperalbuminemia. Although the results indicate a weak protective role for AM, it is nevertheless important for improved erythropoiesis and regulation of the development of anemia. The hepatoprotective role of AM was moderate, and the immune response was not proven. Daily consumption of chokeberry extract can improve health. However, the results of our study showed that the ingestion of AM extract at this dose with the highest AOA would have more effective effects if the supplementation were significantly increased.

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“…Dill is prescribed to alleviate flatulence and promote expulsion of the placenta during delivery, and to stimulate milk flow in lactating mothers. 1,4,5,11,[14][15][16][17][18] Currently, preclinical research has identified antioxidant, antiinflammatory, analgesic, antimicrobial, neuroprotective, and anticancer properties of dill extracts, to name a few. 5,6 Recent clinical trials investigated dill and its extracts for managing risk factors for diabetes and cardiovascular disease, as well as in improving outcomes during labor and delivery.…”

mentioning

confidence: 99%

“…Even now, dill water also known as “gripe water” is commonly used in folk remedies and Ayurvedic medicine to treat digestive and sleep problems, especially in children. Dill is prescribed to alleviate flatulence and promote expulsion of the placenta during delivery, and to stimulate milk flow in lactating mothers 1,4,5,11,14–18 . Currently, preclinical research has identified antioxidant, anti-inflammatory, analgesic, antimicrobial, neuroprotective, and anticancer properties of dill extracts, to name a few 5,6 .…”

mentioning

confidence: 99%

Dill

Singletary¹

2023

Nutr Today

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Anethum graveolens L. (family Apiaceae) is an important culinary herb commonly called dill in English. This plant is native to southwest Asia and the Mediterranean region and is widely cultivated throughout Asia, Africa, Europe, Southern Russia, and the United States. The leaves, fruit, and essential oil of dill have numerous culinary uses, and the oil is a flavor additive in numerous products in the food industry such as dill pickles, processed meat, cheese, and bread. It is a perfume agent in detergents, soaps, fragrances, cosmetics, and mouthwashes. Dill has a long history of use in traditional medicines dating back thousands of years in China, Greece. and the Roman empire, particularly for relieving pain, indigestion, and anxiety. Recent clinical trials evaluated dill and its extracts for managing risk factors for diabetes and cardiovascular disease, as well as in improving outcomes during labor and delivery. This narrative summarizes these published human studies examining the potential health benefits of dill and highlights potential areas for further research.

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Protective Role of Medicinal Herb Anethum Graveolens (Dill) Against Various Human Diseases and Metabolic Disorders

Cited by 6 publications

References 49 publications

The Effect of Extract from Dill Anethum Graveolens on the Growth Performance, Body Composition, Immune System, and Antioxidant System of Rainbow Trout

The Effect of Extract from Dill Anethum Graveolens on the Growth Performance, Body Composition, Immune System, and Antioxidant System of Rainbow Trout

Impact of dietary supplementation with chokeberry (Aronia melanocarpa, Michx.) on tetrachloride‐induced liver injury in Wistar rats: Hematological and biochemical implication

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